This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider.
Brand Names: US
Hympavzi
What is this drug used for?
- It is used to prevent bleeding in people with hemophilia.
What do I need to tell the doctor BEFORE my child takes this drug?
- If your child is allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell the doctor about the allergy and what signs your child had.
This drug may interact with other drugs or health problems.
Tell the doctor and pharmacist about all of your child’s drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe to give this drug with all of your child’s other drugs and health problems. Do not start, stop, or change the dose of any drug your child takes without checking with the doctor.
What are some things I need to know or do while my child takes this drug?
- Tell all of your child’s health care providers that your child is taking this drug. This includes your child’s doctors, nurses, pharmacists, and dentists.
- If your child will be having surgery, talk with the doctor. Your child may need to stop this drug and take another drug to lower the chance of blood clots after surgery.
- If your child has a fever, an infection, or an injury, talk with the doctor. Your child may need to stop this drug for some time.
If your child is or may be sexually active:
- This drug may cause harm to the unborn baby if your child takes it during pregnancy.
- A pregnancy test will be done to show that your child is NOT pregnant before starting this drug. If your child gets pregnant while taking this drug, call the doctor right away.
- If your child may become pregnant, have your child use birth control while taking this drug and for 2 months after the last dose. If your child becomes pregnant, call the doctor right away.
If your child is breast-feeding a baby:
- Tell the doctor if your child is breast-feeding a baby. You will need to talk about any risks to the baby.
What are some side effects that I need to call my child’s doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your child’s doctor or get medical help right away if your child has any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- A fast heartbeat.
- Dizziness or passing out.
- Blood clots may happen with this drug. Tell the doctor if your child has ever had a blood clot. Call the doctor right away if your child has signs of a blood clot like chest pain or pressure; coughing up blood; shortness of breath; swelling, warmth, numbness, skin color change, or pain in a leg or arm; or trouble speaking or swallowing.
What are some other side effects of this drug?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your child’s doctor or get medical help if any of these side effects or any other side effects bother your child or do not go away:
- Pain, redness, swelling, or other reaction where the injection was given.
- Headache.
These are not all of the side effects that may occur. If you have questions about side effects, call your child’s doctor. Call your child’s doctor for medical advice about side effects.
You may report side effects to your national health agency.
How is this drug best given?
Give this drug as ordered by your child’s doctor. Read all information given to you. Follow all instructions closely.
- It is given as a shot into the fatty part of the skin in the upper arm, thigh, buttocks, or stomach area.
- If you will be giving your child the shot, your child’s doctor or nurse will teach you how to give the shot.
- Before using this drug, take it out of the refrigerator. Allow to reach room temperature (15 to 30 minutes). Do not heat this drug.
- This drug is colorless to light yellow. Do not use if the solution turns dark yellow or any other color, is cloudy, leaking, or has flakes or particles.
- If you see a small air bubble in the device, do not get rid of it.
- Do not shake.
- Do not give into skin within 2 inches (5 cm) of the belly button.
- Do not give into bony areas.
- Do not give into skin that is irritated, tender, bruised, red, scaly, hard, scarred, or has stretch marks.
- Move the site where you give the shot with each shot.
- If your child’s dose is more than 1 injection, give each injection in a different area.
- If your child is also getting another drug as a shot under the skin, use this drug in a different area of the body if possible.
- Throw away after using. Do not use the device more than 1 time.
- Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
What do I do if my child misses a dose?
150 mg maintenance dose:
- Give a missed dose as soon as you think about it.
- After giving a missed dose, keep giving on your child’s normal day or start a new schedule based on the day the dose is taken.
- If it has been more than 13 days since your child’s last dose, call your child’s doctor to find out what to do.
300 mg maintenance dose:
- Give a missed dose as soon as you think about it.
- After giving a missed dose, keep giving on your child’s normal day or start a new schedule based on the day the dose is taken.
All products:
- Do not give 2 doses on the same day.
- If you are not sure what to do if your child misses a dose, call the doctor.
How do I store and/or throw out this drug?
- Store in a refrigerator. Do not freeze.
- Do not use if it has been frozen.
- Store in the original container to protect from light.
- If needed, this drug may be stored at room temperature for up to 7 days. If stored at room temperature and not used within 7 days, throw this drug away.
- Do not put this drug back in the refrigerator after it has been stored at room temperature.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
General drug facts
- If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
- Do not share your child’s drug with others and do not give anyone else’s drug to your child.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Consumer Information Use and Disclaimer
This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. It is not intended to be medical advice or a substitute for the medical advice, diagnosis, or treatment of a health care provider based on the health care provider’s examination and assessment of a patient’s specific and unique circumstances. Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. This information does not endorse any treatments or medications as safe, effective, or approved for treating a specific patient. UpToDate, Inc. and its affiliates disclaim any warranty or liability relating to this information or the use thereof. The use of this information is governed by the Terms of Use, available at https://www.wolterskluwer.com/en/know/clinical-effectiveness-terms.
Last Reviewed Date
2024-10-17
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