Zoliflodacin

Pediatric Medication

This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider.

What is this drug used for?

  • It is used to treat gonorrhea.

What do I need to tell the doctor BEFORE my child takes this drug?

  • If your child is allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell the doctor about the allergy and what signs your child had.
  • If your child takes any drugs (prescription or OTC, natural products, vitamins) that must not be taken with this drug, like certain drugs that are used for HIV, infections, seizures, and others. There are many drugs that must not be taken with this drug.

If your child is or may be pregnant:

  • This drug may cause harm to an unborn baby. Do not give this drug to your child during pregnancy.

This is not a list of all drugs or health problems that interact with this drug.

Tell the doctor and pharmacist about all of your child’s drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe to give this drug with all of your child’s other drugs and health problems. Do not start, stop, or change the dose of any drug your child takes without checking with the doctor.

What are some things I need to know or do while my child takes this drug?

  • Tell all of your child’s health care providers that your child is taking this drug. This includes your child’s doctors, nurses, pharmacists, and dentists.
  • Your child must have a pregnancy test to show that she is NOT pregnant before starting this drug.
  • This drug may be harmful to testicles and may lower sperm counts. This may affect being able to father a child. If you have questions, talk with the doctor.

If your child is or may be sexually active:

  • If your child’s sex partner may become pregnant, birth control must be used for at least 3 months after your child takes this drug. If your child’s partner gets pregnant, call the doctor right away.

If your child is breast-feeding a baby:

  • Tell the doctor if your child is breast-feeding a baby. You will need to talk about any risks to the baby.

What are some side effects that I need to call my child’s doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your child’s doctor or get medical help right away if your child has any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Fever, chills, or sore throat.
  • A severe form of diarrhea called C diff-associated diarrhea (CDAD) has happened with most antibiotics. Sometimes, this can be deadly. This may happen while using the antibiotic or within a few months after your child stops using it. Call the doctor right away if your child has stomach pain or cramps, very loose or watery stools, or bloody stools. Do not try to treat diarrhea without first checking with the doctor.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your child’s doctor or get medical help if any of these side effects or any other side effects bother your child or do not go away:

  • Dizziness or headache.
  • Upset stomach.
  • Diarrhea.

These are not all of the side effects that may occur. If you have questions about side effects, call your child’s doctor. Call your child’s doctor for medical advice about side effects.

You may report side effects to your national health agency.

How is this drug best given?

Give this drug as ordered by your child’s doctor. Read all information given to you. Follow all instructions closely.

For all people taking this drug:

  • Mix with water as told before you give this drug. Be sure your child does not swallow the dry powder.
  • Do not mix with other liquids.
  • Do not sprinkle this drug on food.
  • Give the dose within 15 minutes after mixing. If not given within 15 minutes of mixing, throw it away and call the doctor to get a new dose.
  • If your child is not able to take the full dose, call the doctor to find out what to do.

People who weigh between 77 to 110 pounds (35 to 50 kg):

  • Give this drug on an empty stomach. Give at least 1 hour before or 2 hours after your child eats.

People who weigh 110 pounds (50 kg) or more:

  • Give this drug with food.

What do I do if my child misses a dose?

  • Only 1 dose of this drug is needed. If your child missed the dose, give it as soon as you think about it.

How do I store and/or throw out this drug?

  • Store at room temperature. Do not freeze.
  • Store in the original package until you are ready to use.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.

General drug facts

  • If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
  • Do not share your child’s drug with others and do not give anyone else’s drug to your child.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. It is not intended to be medical advice or a substitute for the medical advice, diagnosis, or treatment of a health care provider based on the health care provider’s examination and assessment of a patient’s specific and unique circumstances. Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. This information does not endorse any treatments or medications as safe, effective, or approved for treating a specific patient. UpToDate, Inc. and its affiliates disclaim any warranty or liability relating to this information or the use thereof. The use of this information is governed by the Terms of Use, available at https://www.wolterskluwer.com/en/know/clinical-effectiveness-terms.

Last Reviewed Date

2025-12-15

Copyright

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Last Updated

December 20, 2025

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