Recombinant Human TSH and Radioactive Iodine Treatment: 3-Week Regimen

This information describes the 3-week regimen for your recombinant human thyroid stimulating hormone (TSH) regimen. A regimen is a course of treatment.

Treatment with radioactive iodine helps lower the risk that thyroid cancer will come back. It’s also used to treat thyroid cancer that has spread.

Your nurse will give you more information about how to prepare and what to expect during and after your treatment.

Follow a Low-Iodine Diet

You will need to follow a low-iodine diet before your regimen. Your nurse will give you a resource called Low Iodine Diet that has more instructions.

Start following the low-iodine diet ___ days before day 1 of your regimen.

Drink at least 8 (8-ounce) glasses of decaffeinated liquids every day. The liquids should include water and other beverages listed in the low-iodine diet guidelines.

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Regimen Schedule

During the first week of your regimen, you will come to the hospital Monday through Saturday. You will have blood tests, scans, and injections (shots) of recombinant human TSH.

During the second week of your regimen, you will receive your treatment.

During the third week of your regimen, you will have a post-treatment scan. A staff member in Nuclear Medicine will arrange this for you.

Below is a typical regimen schedule:

Week 1
Diagnostic
Testing
Day 1 
(2 to 3 hours)
•Blood tests
•Recombinant human TSH injection
Day 2 
(30 to 60 minutes)
•Recombinant human TSH injection
Day 3
(4 to 6 hours)
•Blood tests
•Diagnostic dose of radioactive iodine
•Radiation measure
Day 4
(90 minutes)
•Blood tests
•Scan
•Radiation measure
Day 5
(90 minutes)
•Blood tests
•Scan
•Radiation measure
Day 6
(90 minutes)
•Blood tests
•Scan
•Radiation measure
Week 2
Treatment
(May start
Tuesday,
Wednesday,
or Thursday)
Day 2
(30 minutes)
•Recombinant human TSH injection
Day 3
(30 minutes)
•Recombinant human TSH injection
Day 4
•Treatment dose of radioactive iodine
•Scan
Week 3
Follow-up
Post-treatment scan
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