James Allison Elected to the Institute of Medicine

Pictured: James Allison

James Allison, PhD -- Chair, Immunology Program

James P. Allison, Chair of the Immunology Program in the Sloan Kettering Institute, has been elected a member of the Institute of Medicine. Dr. Allison is also a Howard Hughes Medical Institute investigator, a member of the National Academy of Sciences, and the incumbent of the David H. Koch Chair in Immunologic Studies at Memorial Sloan Kettering.

Dr. Allison is a leader in the field of immunology, particularly in developing ways to help the immune system recognize and destroy cancer cells. His research is focused on the mechanisms that regulate the immunological response of T lymphocytes, especially strategies to manipulate those responses in clinically relevant areas, including autoimmunity, allergies, vaccinations, and tumor therapy. Dr. Allison has shown that an immune-regulating molecule called cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) inhibits activated T cells in the immune system and prevents them from attacking the body’s own tissues. In mouse models, he identified an antibody that blocks CTLA-4 and showed that it enhances the cancer-fighting activity of certain vaccines. He and his colleagues have now created antibodies to human CTLA-4 that are being studied in human clinical trials for the treatment of melanoma, renal cell carcinoma, prostate cancer, and ovarian cancer.

The Institute of Medicine is a branch of the National Academies and was established to honor professional achievement in the health sciences and to serve as a national resource for recommendations on issues related to medicine, biomedical sciences, and health. Eleven members of Memorial Sloan Kettering’s staff are already members of the Institute of Medicine.


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Dear Doctors/Researchers,
My name is Madhumita Suresh and I am pursuing my Master’s degree from Keck Graduate Institute of the Claremont Colleges. As part of my Master's thesis team project, I have been tasked to assess trends in Immuno-Oncology and applications in diagnostics. I have identified you guys as influential opinion leaders in the field of Immuno-Oncology and was hoping to get your help with this project.

I would like to propose a short (~15 min) phone interview with any of you to get your view on the developments within the field of Immuno-Oncology.

I understand you are busy, but your time and cooperation will be greatly valued in helping me to complete this project for my degree. Would your calendar allow a 15 min time slot on Friday, March 30th, between 1:00 and 6:00 PM PST? Or, another option might be on Monday, April 2nd between 1:00 and 6:00 PM PST. If neither of these are good moments for you, please send me times that work best with your schedule and I will adjust my schedule accordingly.

I would be readily available even during weekends if that works better with your schedule.

Thank you very much in advance for your time and consideration.

Madhumita Suresh

Dear Madhumita, we recommend you reach out to our Media Staff at mediastaff@mskcc.org to see if they are able to arrange this interview for you. Thank you for your interest in MSK.