Prediction Tools: Disclaimer
The prediction tools, also known as prognostic nomograms, located on the MSKCC Web site are for general health information only. The prediction tools are not to be used as a substitute for medical advice, diagnosis, or treatment of any health condition or problem.
Users of the prediction tools should not rely on information provided by the prediction tools for their own health problems. Questions should be addressed to your own physician or other healthcare provider.
MSKCC makes no warranties, nor express or implied representations whatsoever, regarding the accuracy, completeness, timeliness, comparative or controversial nature, or usefulness of any information contained or referenced in the prediction tools. MSKCC does not assume any risk whatsoever for your use of the prediction tools or the information contained herein. Health related information changes frequently and therefore information contained in the prediction tools may be outdated, incomplete or incorrect.
Use of the prediction tools does not create an express or implied physician-patient relationship. MSKCC does not endorse or claim validity for the prediction tools found on the MSKCC Web site. The activities and products of MSKCC and its developers and agents (collectively MSKCC) are not endorsed by our past, present, or future employers. MSKCC does not record specific prediction tool user information and does not contact users of the prediction tools.
You are hereby advised to consult with a physician or other professional healthcare provider prior to making any decisions, or undertaking any actions or not undertaking any actions related to any healthcare problem or issue you might have at any time, now or in the future. In using the prediction tools, you agree that neither MSKCC nor any other party is or will be liable or otherwise responsible for any decision made or any action taken or any action not taken due to your use of any information presented in the prediction tools.
This tool is intended to identify patients at risk for developing serious drug-related toxicity (SDRT) in the first cycle so that physicians can assess a patient’s baseline risk for SDRT before a decision is made about participation in a phase I clinical trial. It is appropriate for patients who do not have leukemia or lymphoma and who are entering trials where they will be treated with cytotoxic or molecularly targeted agents, alone or in combination. It is not appropriate for patients entering clinical trials testing vaccines, radiation therapy, or loco-regional therapy (therapy that affects only a specific area rather than the whole body [systemic]), or for patients on dedicated organ dysfunction trials.
In addition, patients must:
Be 18 years of age or more
Have solid tumors
Have an absolute neutrophil count of at least 1 x 10
9/L Have a hemoglobin level of at least 8 g/dL
Have a platelet count of at least 75 x 10
9/L Have aspartate aminotransferase (AST) equal to or less than 5 x upper limit of normal (ULN), alanine aminotransferase (ALT) equal to or less than 5 x ULN, and total bilirubin equal to or less than 2 x ULN
Results produced by this tool are based on data from more than 3,100 patients enrolled in 127 phase I trials sponsored by the National Cancer Institute’s Cancer Therapeutics Evaluation Program (CTEP). All results must be understood in the context of each patient’s specific treatment plan. If you are a patient, we recommend that you use this tool ONLY in consultation with your physician.