Recent MSK Discoveries & Advances

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Memorial Sloan Kettering researchers are relentlessly exploring every aspect of cancer — from basic investigations of cells and molecules to clinical trials of new treatments and population-wide studies of the disease. While our core mission is to translate this knowledge into new strategies to control cancer, many of our investigators are also making scientific progress against other diseases and conditions.

Below are some examples of discoveries and advances that recently were made in our laboratories and clinics, and featured in our news stories.

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373 News Items found
In the Lab
Physician-scientist Omar Abdel-Wahab in his lab.
Targeting Errors in How Proteins Are Made Is a Promising Approach for Cancer Treatment

MSK studies look at the role of RNA splicing factors in acute myeloid leukemia and melanoma.
In the Lab
Blue cells on a black background
Scientists Create the First Human-Tumor-Derived Model for Studying Rectal Cancer

Scientists at Memorial Sloan Kettering have created a model of rectal cancer using human-tumor-derived organoids.
Finding
Red blood cells
Research Points to a Potential New Approach for Treating Anemia

A class of drugs originally developed to treat certain neurological disorders appears to boost the production of red blood cells.
Q&A
Pediatric oncologist Julia Glade Bender
Meet Julia Glade Bender, Who’s Focused on Developing Better Treatments for Kids with Cancer

Pediatric oncologist Julia Glade Bender talks about the challenges of treating rare childhood cancers and how personalized medicine is leading to better therapies for tumors that are especially hard to treat.
In the Lab
illustration of the p53 protein binding to a DNA helix
New Findings Clarify How the “Guardian of the Genome” Works

Surprise! It has to do with metabolism.
Finding
A micrograph of a cell nucleus
How an Altered Gatekeeping Protein Can Cause Cancer

An MSK study explains how the drug selinexor, which was recently approved to treat multiple myeloma and is being tested in many other tumor types, stops cancer.
Finding
Medical oncologist Elizabeth Comen
What Causes Leukemia after Breast Cancer? Research Shows That a Mutation May Be Present All Along

A study from MSK takes a deeper look at some of the causes of secondary leukemia.
Finding
a man holding a shield and sword
Scientists See Potential in Cellular 'Death by Iron' for Cancer Treatment

This form of cell death is called ferroptosis, and certain cancer cells are especially vulnerable to it.
In the Lab
Microscopy image of vancomycin-resistant Enterococcus
Researchers Identify a Bacterial Species That Could Protect against Hospital-Acquired Infections

MSK researchers are reporting that a bacterial species called Blautia producta appears to release a substance that kills harmful bacteria.
In the Lab
An illustration of two teapots with liquid flowing into various cups
How Stem Cells Decide Their Fate

Research in blood stem cells has revealed new information about how these cells decide what to become when they divide.