Jake Lee, MD, PhD, is an Assistant Member in the Computational Oncology Service, where his research focuses on mutational processes in cancer, with particular emphasis on the mechanisms driving genomic rearrangements. Born and raised in Seoul, South Korea, he earned his MD from Seoul National University, where he also completed an internal medicine residency, followed by a PhD in Cancer Genomics at the Korea Advanced Institute of Science and Technology (KAIST). He subsequently moved to the United States for postdoctoral training in Prof. Peter Park’s laboratory at Harvard Medical School and completed a second internal medicine residency at Brigham and Women’s Hospital. He then relocated to New York City for a medical oncology fellowship at Memorial Sloan Kettering Cancer Center (MSK), where he established his research group in July 2025.
Through his work at Harvard Medical School, Dr. Lee made key discoveries elucidating the mechanisms underlying oncogene amplifications and gene fusions in breast and lung cancers. At MSK, he expanded these studies to the single-cell level in collaboration with his mentor, Prof. Sohrab Shah. In recognition of his contributions, he received the Burroughs Wellcome Fund Career Award for Medical Scientists in 2024 and an NCI K08 award in 2025. He also takes care of patients with lung cancer, as part of Thoracic Oncology Service at MSK. As a clinical investigator, his work has also advanced the understanding of targeted therapies in lung cancer and the mechanisms driving therapeutic resistance.
Disclosures
Members of the MSK Community often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community. These activities outside of MSK further our mission, provide productive collaborations, and promote the practical application of scientific discoveries.
MSK requires doctors, faculty members, and leaders to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public. Not all disclosed interests and relationships present conflicts of interest. MSK reviews all disclosed interests and relationships to assess whether a conflict of interest exists and whether formal COI management is needed.
Jake June-Koo Lee discloses the following relationships and financial interests:
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