Human Oncology & Pathogenesis Program

The Alan Hanash Lab

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Research

Alan M. Hanash, MD, PhD
Alan M. Hanash, MD, PhD

Alan Hanash is an Assistant Member of Memorial Sloan Kettering and an Attending Physician on the Adult Bone Marrow Transplant Service in the Department of Medicine. Dr. Hanash’s research focuses on the immunology of hematopoietic transplantation and immune-mediated mechanisms of tissue damage and regeneration.

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The Alan Hanash Lab

Featured News

In the Lab
This cross section of a mouse intestine shows dividing cells (stained white) in the epithelial layer of the intestine, which lines the organ. These proliferating cells help restore intestinal tissue after damage from graft-versus-host disease (GVHD).
Immune System Molecule Could Become New Treatment for Graft-Versus-Host Disease

Scientists are using a molecule from the immune system to combat this serious complication in a new way.

Publications

Lindemans CA*, Calafiore M*, Mertelsmann AM*, O’Connor MH*, Dudakov JA, Jenq RR, Velardi E, Young LF, Smith OM, Lawrence G, Ivanov JA, Fu Y, Takashima S, Hua G, Martin ML, O’Rourke KP, Lo Y, Mokry M, Romera-Hernandez M, Cupedo T, Dow L, Nieuwenhuis EE, Shroyer NF, Liu C, Kolesnick R, van den Brink MRM*, and Hanash AM*. Interleukin-22 Promotes Intestinal Stem Cell-Mediated Epithelial Regeneration. Nature. 2015 Dec 24;528(7583): 560-4.

Interleukin-22: immunobiology and pathology. Dudakov JA, Hanash AM, van den Brink MR. Annu Rev Immunol. 2015 Mar 21;33:747-85. doi: 10.1146/annurev-immunol-032414-112123. Epub 2015 Feb 11.

Geiger TL, Abt MC, Gasteiger G, Firth M, O’Connor M, van den Brink MR, Pamer EG, Hanash AM*, Sun JC*. Nfil3 is crucial for development of innate lymphoid cells and host protection against intestinal pathogens. J Exp Med. 2014 Aug 25;211(9):1723-31.

Hanash AM, Kappel LW, Yim NL, Nejat RA, Goldberg GL, Smith OM, Rao UK, Dykstra L, Na IK, Holland AM, Liu C, Murphy GF, Leonard WJ, Heller G, van den Brink MR. Abrogation of donor T cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL. Blood. 2011 Jul 14;118(2):446-55.

Hanash AM. MataHari reveals secrets of GVHD. Blood. 2012 Apr 19;119(16):3656-7.

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People

Alan M. Hanash, MD, PhD

Alan M. Hanash, MD, PhD

  • Physician-scientist Alan Hanash studies transplant immunology and immune-mediated mechanisms of tissue damage and regeneration.
  • MD, University of Miami
[email protected]
Email Address
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Physician profile

Members

Diana Achaibar
Diana Achaibar

Office Coordinator

Viktor Arnhold
Viktor Arnhold

Research Fellow

Marco Calafiore
Marco Calafiore

Senior Researcher

Winston Chang
Winston Chang
Anastasiya Egorova
Anastasiya Egorova

Senior Research Technician

Ya-Yuan Fu
Ya-Yuan Fu

Postdoctoral Researcher

Takahiro Ito
Takahiro Ito

Visiting Investigator

Jason Kuttiyara
Jason Kuttiyara

Research Technician

Shuichiro Takashima
Shuichiro Takashima

Research Fellow

Paola Vinci
Paola Vinci

Research Fellow

Lab Alumni
Gillian Lawrence
Gillian Lawrence

Research Technician

Margaret O'Connor
Margaret O'Connor

Research Technician

Orit Ben-David

Volunteer

Niccolo Bordignon

Volunteer

Daniel Chandra
Daniel Chandra

Graduate Research Assistant

Robert Emmet

Intern

Elena Garcia-Martinez, MD
Elena Garcia-Martinez

Research Fellow

Maheen Iqbal

Volunteer

Juliet Ivanov
Juliet Ivanov

Volunteer

Suze Jansen
Suze Jansen

NE Intern

Perry Kerner

Volunteer

Anna Mertelsmann
Anna Mertelsmann

Research Fellow

Lorenzo Muranelli
Lorenzo Muranelli
Eileen Nicoletti
Eileen Nicoletti

Clinical Fellow

Pranav Parsi

Intern

Johanna Pinto Lee

NE Intern

Ankita Prakash

Volunteer

Sobhana Sripada

Volunteer

Kelsey Topa
Kelsey Topa

Administrative Assistant

Murshea Tuor

Intern

Lab Affiliations

Achievements

  • ASCI Young Physician-Scientist Award (2014)
  • Amy Strelzer Manasevit Research Program Scholar (2014)
  • ASH Outstanding Abstract Achievement Award for Anna Mertelsmann (2013)
  • ASH Scholar Award for Junior Faculty (2012)
  • ASBMT New Investigator Award (2011)

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Alan M. Hanash discloses the following relationships and financial interests:

  • Evive Biotech
    Provision of Services (uncompensated)
  • Generon (Shanghai) Corporation Ltd.
    Provision of Services (uncompensated)

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.

This page and data include information for a specific MSK annual disclosure period (January 1, 2021 through disclosure submission in spring 2022). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].


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