Quintanal-Villalonga A, Durani V, Sabet A, Redin E, Kawasaki K, Shafer M, Karthaus WR, Zaidi S, et al. Exportin 1 inhibition prevents neuroendocrine transformation through SOX2 down-regulation in lung and prostate cancers. Sci Transl Med. (2023)

Rudin CM, Balli D, Lai WV, Richards AL, Nguyen E, Egger JV, Choudhury NJ, Sen T, Chow A, Poirier JT, Geese WJ, Hellmann MD, Forslund A. Clinical Benefit From Immunotherapy in Patients With SCLC Is Associated With Tumor Capacity for Antigen Presentation. J Thorac Oncol. (2023)

Jaspers JE, Khan JF, Godfrey WD, Lopez AV, Ciampricotti M, Rudin CM, Brentjens RJ. IL-18-secreting CAR T cells targeting DLL3 are highly effective in small cell lung cancer models. J Clin Invest. (2023).

Chow A, Uddin FZ, Liu M, Dobrin A, Nabet BY, Mangarin L, Lavin Y, Rizvi H, Tischfield SE, Quintanal-Villalonga A, Chan JM, et al. The ectonucleotidase CD39 identifies tumor-reactive CD8⁺ T cells predictive of immune checkpoint blockade efficacy in human lung cancer. Immunity. (2023) 

Chemi F, Pearce SP, Clipson A, Hill SM, Conway AM, Richardson SA, Kamieniecka K, Caeser R, et al. cfDNA methylome profiling for detection and subtyping of small cell lung cancers. Nat Cancer. (2022) 

Rudin CM, Brambilla E, Faivre-Finn C, Sage J. Small-cell lung cancer. Nat Rev Dis Primers. (2021)

Quintanal-Villalonga A, Taniguchi H, Zhan YA, Hasan MM, Chavan SS, Meng F,Uddin F, Manoj P, et al. Multi-omic analysis of lung tumors defines pathways activated in neuroendocrine transformation. Cancer Discov. (2021)

 Tully KM, Tendler S, Carter LM, Sharma SK, et al. Radioimmunotherapy Targeting Delta-like Ligand 3 in SmallCell Lung Cancer Exhibits Antitumor Efficacy with Low Toxicity. Clin Cancer Res. (2022)

Chow, A., Schad, S., Green, M., Hellmann, M.D., Allaj, V., et al. Tim-4+ cavity-resident macrophages impair anti-tumor CD8+ T cell immunity. Cancer Cell (2021).

Caeser R, Hulton C, Costa E, Durani V, Little M, et. al. MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer. iScience (2021).

Chan JM, Quintanal-Villalonga Á, Gao VR, Xie Y, Allaj V, et al. Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer. Cancer Cell 2021.

Quintanal-Villalonga A, Taniguchi H, Zhan YA, Hasan MM, Chavan SS, Meng F, Uddin F, et al. Comprehensive molecular characterization of lung tumors implicates AKT and MYC signaling in adenocarcinoma to squamous cell transdifferentiation. J Hematol Oncol (2021).

Ciampricotti M, Karakousi T, Richards AL, Quintanal-Villalonga À, Karatza A, Caeser R, Costa EA, et al. Rlf-Mycl Gene Fusion Drives Tumorigenesis and Metastasis in a Mouse Model of Small Cell Lung Cancer. Cancer Discover (2021).

Quintanal-Villalonga A, Taniguchi H, Zhan YA, Hasan MM, Chavan SS, Meng F, Uddin F, Manoj P, et al. Multi-omic analysis of lung tumors defines pathways activated in neuroendocrine transformation. Cancer Discov (2021)

Chow, A., Schad, S., Green, M., Hellmann, M.D., Allaj, V., et al. Tim-4+ cavity-resident macrophages impair anti-tumor CD8+ T cell immunity. Cancer Cell (2021).

Hulton, C. H., Costa, E. A., Shah, N. S., Quintanal-Villalonga, A., Heller, G., de Stanchina, E., Rudin, C. M. & Poirier, J. T. Direct genome editing of patient-derived xenografts using CRISPR-Cas9 enables rapid in vivo functional genomics. Nat Cancer 1, 359-369 (2020).

Wohlhieter, C. A., Richards, A. L., Uddin, F., Hulton, C. H., Quintanal-Villalonga, A., Martin, A., de Stanchina, E., Bhanot, U., Asher, M., Shah, N. S., Hayatt, O., Buonocore, D. J., Rekhtman, N., Shen, R., Arbour, K. C., Donoghue, M., Poirier, J. T., Sen, T. & Rudin, C. M. Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer. Cell Rep 33, 108444 (2020).

Quintanal-Villalonga, A., Chan, J. M., Yu, H. A., Pe’er, D., Sawyers, C. L., Sen, T. & Rudin, C. M. Lineage plasticity in cancer: a shared pathway of therapeutic resistance. Nat Rev Clin Oncol 17, 360-371 (2020).

Taniguchi, H., Sen, T. & Rudin, C. M. Targeted Therapies and Biomarkers in Small Cell Lung Cancer. Front Oncol 10, 741 (2020).