The Charles Rudin Lab

The Charles Rudin Lab

Physician-scientist Charles M. Rudin, Chief of the Thoracic Oncology Service, leads research that focuses on the development and testing of novel therapeutic approaches to lung cancer in preclinical models including patient-derived xenografts. These studies are integrated with early phase clinical trials.

Pictured: Charles Rudin

Charles M. Rudin, MD, PhD

Research Focus

Physician-scientist Charles Rudin focuses on the development and testing of novel therapeutic approaches to lung cancer in preclinical models.

Lab Members

Publications

  • Poirier JT, Gardner EE, Connis N, Moreira AL, de Stanchina E, Hann CL, Rudin CM.  DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2.  Oncogene 2015; in press.
  • Vendetti FP, Topper M, Huang P, Dobromilskaya I, Easwaran H, Wrangle J, Baylin SB, Poirier JT, Rudin CM.  Evaluation of azacitidine and entinostat as sensitization agents tocytotoxic chemotherapy in preclinical models of non-small cell lung cancer.  Oncotarget 2015; 6:57-70.
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Career Opportunities

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