The focus of my research is concentrated on detection and molecular characterization of prognostic markers in soft tissue sarcomas. More specifically, a significant effort in my lab is dedicated to the characterization of molecular mechanisms of pathogenesis and drug resistance in gastrointestinal stromal tumors (GIST).
Cristina R. Antonescu, MD
Research FocusPhysician-scientist Cristina Antonescu studies the molecular pathogenesis of soft tissue sarcomas and gastrointestinal stromal tumors.
- Antonescu CR, Tschernyavsky SJ, Decuseara R, Leung DH, Woodruff JM, Brennan MF, Bridge JA, Neff JR, Goldblum JR, Ladanyi M. Prognostic Impact of P53 Status, TLS-CHOP Fusion Transcript Structure, and Histological Grade in Myxoid Liposarcoma: A Molecular and Clinicopathologic Study of 82 Cases. Clin Cancer Res 2001; 7:3977-87.
- Khan J, Wei JS, Ringner M, Saal LH, Ladanyi M, Westermann F, Berthold F, Schwab M, Antonescu CR, Peterson C, Meltzer PS. Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks. Nat Med 2001; 7:673-679.