Genomics Define Malignant Transformation in Myeloma Precursor Conditions. Maura F*, Bergsagel PL, Ziccheddu B, Kumar S, Maclachlan K, Derkach A, Garces JJ, Firestone R, Braggio E, Asmann Y, Durante M, Diamond B, Papadimitriou M, Hultcrantz M, Marella A, Castellano G, Maeda A, Lionetti M, Matera A, Pioggia S, Da Vià MC, de Magistris C, Leongamornlert D, DeAvila D, Sudalagunta PR, Renatino Canevarolo R, Siegel E, Agius P, Teer J, McPherson A, Yamashita Y, Silva A, Blaney P, Baz R, Patel KK, Campbell P, Morgan G, Fonseca R, Landgren O, Orlowski RZ, Shain KH, Bolli N, Usmani S, Rajkumar SV. J Clin Oncol. 2026 Jan 20;44(3):188-199. doi: 10.1200/JCO-25-01733. Epub 2025 Oct 8. (*Corresponding author) [PMID: 41061199]
Temporal genomic dynamics shape clinical trajectory in multiple myeloma. Francesco Maura*, Marcella Kaddoura*, Alexandra M. Poos*, Linda B. Baughn, Bachisio Ziccheddu, Marc-Andrea Bärtsch, Anthony Cirrincione, Kylee Maclachlan, Monika Chojnacka, Benjamin Diamond, Marios Papadimitriou, Patrick Blaney, Lukas John, Philipp Reichert, Stefanie Huhn, Dylan Gagler, Yanming Zhang, Ahmet Dogan, Alexander M Lesokhin, Faith Davies, Hartmut Goldschmidt, Roland Fenk, Katja C. Weisel, Elias K. Mai, Neha Korde, Gareth J Morgan, S. Vincent Rajkumar, Shaji Kumar, Saad Usmani, Ola Landgren, Marc S. Raab*, Niels Weinhold*. Nat Genet. 2025 Aug 20. doi: 10.1038/s41588-025-02292-1. PMID: 40835892. (*Corresponding author)
Biallelic antigen escape is a mechanism of resistance to anti-CD38 antibodies in multiple myeloma. Benjamin Diamond, Linda Baughn, Mansour Poorebrahim, Alexandra M. Poos, Holly Lee, Marcella Kaddoura, J. Erin Wiedmeier-Nutor, Michael Durante, Gregory Otteson, Dragan Jevremovic, Hongwei Tang, Stefan Fröhling, Marc A. Baertsch, Marios Papadimitriou, Bachisio Ziccheddu, Tomas Jelinek, Cendrine Lemoine, Alexey Rak, Damian J. Green, Ola Landgren, Paola Ner3, Leif Bergsagel, Esteban Braggio, Shaji Kumar, Marc S. Raab, Rafael Fonseca, Nizar Bahlis, Niels Weinhold, Francesco Maura. Blood 2025 Jun 10:blood.2024028107. doi: 10.1182/blood.2024028107. PMID: 40493883 (*Corresponding author)
Genomic Classification and Individualized Prognosis in Multiple Myeloma. Maura F*, Rajanna AR, Ziccheddu B, Poos AM, Derkach A, Maclachlan K, Durante M, Diamond B, Papadimitriou M, Davies F, Boyle EM, Walker B, Hultcrantz M, Silva A, Hampton O, Teer JK, Siegel EM, Bolli N, Jackson GH, Kaiser M, Pawlyn C, Cook G, Kazandjian D, Stein C, Chesi M, Bergsagel L, Mai EK, Goldschmidt H, Weisel KC, Fenk R, Raab MS, Van Rhee F, Usmani S, Shain KH, Weinhold N, Morgan G, Landgren O.J Clin Oncol. 2024 Jan 9:JCO2301277. doi: 10.1200/JCO.23.01277. PMID: 38194610. (*Corresponding author)
Mechanisms of antigen escape from BCMA- or GPRC5D-targeted immunotherapies in multiple myeloma. Lee H, Ahn S, Maity R, Leblay N, Ziccheddu B, Truger M, Chojnacka M, Cirrincione A, Durante M, Tilmont R, Barakat E, Poorebrahim M, Sinha S, McIntyre J, M Y Chan A, Wilson H, Kyman S, Krishnan A, Landgren O, Walter W, Meggendorfer M, Haferlach C, Haferlach T, Einsele H, Kortüm MK, Knop S, Alberge JB, Rosenwald A, Keats JJ, Rasche L, Maura F*, Neri P, Bahlis NJ.Nat Med. 2023 Sep;29(9):2295-2306. doi: 10.1038/s41591-023-02491-5. Epub 2023 Aug 31.PMID: 37653344. (*Corresponding and co-senior author)
