The John Humm Lab

I am head of the nuclear medicine physics section, which supports research in PET/CT, targeted therapies, and molecular imaging. As both a medical and biophysicist, I investigate nuclear imaging methodologies to define tumor targets in terms of their metabolic and microenvironmental properties. I have a special interest in the quantitative imaging of tumor hypoxia — a known factor in determining resistance to treatment — and in ways of precisely delivering radiotherapy to a tumor, including targeting radionuclides using antibodies that can home in on cancer cells to provide a diagnostic image as well as deposit a therapeutic dose.