Jessica Rios-Esteves, PhD

Project Manager MS&T at Novartis Morris Plains, NJ

Dissertation

Fatty Acylation of WNT Proteins by the Acyltranferase Porcupine

Mentor

Marilyn Resh, PhD

End Year

2014

Education

University of Puerto Rico at Mayagüez

Publications

Rios-Esteves J, Haugen B, Res M. (2014) Identification of Key Residues and Regions Important for Porcupine-mediated Wnt Acylation. J Biol Chem, 289, 17009-17019. PMCID: PMC4059143.

Petrova E, Rios-Esteves J, Ouerfelli O, Glickman J, Resh M. (2013) Inhibitors of Hedgehog acyltransferase block Sonic Hedgehog signaling. Nat Chem Biol, 9, 247-249. PMCID: PMC3604071.

Rios-Esteves J, Resh M. (2013) Stearoyl CoA desaturase is required to produce active, lipid-modified Wnt proteins. Cell Rep, 4, 1072-1081. PMCID: PMC3845236.