Jessica Rios-Esteves, PhD

Technical Program Lead, Legend Biotech, Piscataway, NJ

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Jessica Rios-Esteves, PhD

Technical Program Lead, Legend Biotech, Piscataway, NJ

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Jessica Rios Estevez

Dissertation

Fatty Acylation of WNT Proteins by the Acyltranferase Porcupine (2014)

Mentor

Marilyn Resh, PhD

End Year

2014

Education

University of Puerto Rico at Mayagüez

Publications

Rios-Esteves J, Haugen B, Res M. (2014) Identification of Key Residues and Regions Important for Porcupine-mediated Wnt Acylation. J Biol Chem, 289, 17009-17019. PMCID: PMC4059143.

Petrova E, Rios-Esteves J, Ouerfelli O, Glickman J, Resh M. (2013) Inhibitors of Hedgehog acyltransferase block Sonic Hedgehog signaling. Nat Chem Biol, 9, 247-249. PMCID: PMC3604071.

Rios-Esteves J, Resh M. (2013) Stearoyl CoA desaturase is required to produce active, lipid-modified Wnt proteins. Cell Rep, 4, 1072-1081. PMCID: PMC3845236.