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Sloan Kettering Institute
Research
- - Changing how the world understands and treats cancer
    Our scientists pursue every aspect of cancer research—from exploring the biology of genes and cells, to developing immune-based treatments, uncovering the causes of metastasis, and more.
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  - Sloan Kettering Institute
    Pursuing basic and translational research across 9 programs and 100+ labs
  - Memorial Hospital research
    Focusing on clinical cancer research and population health
  - Human Oncology & Pathogenesis Program (HOPP)
    Bridging the lab and the clinic through translational research
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- - Training the next generation of clinicians and scientists
    Our highly-specialized educational programs shape leaders to be at the forefront of cancer care and research.
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    Memorial Sloan Kettering was founded in 1884, and today is a world leader in patient care, research, and educational programs.
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- Sloan Kettering Institute
- Research
  - - Programs & Centers
    - Sloan Kettering Institute
      Pursuing basic and translational research across 9 programs and 100+ labs
    - Memorial Hospital research
      Focusing on clinical cancer research and population health
    - Human Oncology & Pathogenesis Program (HOPP)
      Bridging the lab and the clinic through translational research
    - Collaborative research centers
      Fostering interdisciplinary collaborations between laboratory scientists and clinicians
    - Extramural collaborations
      Partnering with other academic and research institutions
  - - Research at MSK
    - Our research impact
    - Research topics
    - Core facilities & resources
      Offering state-of-the-art resources for our researchers
    - Find a researcher or lab
    - Education & training programs
- Education & Training
  - - For Research
    - Postdoctoral training
    - Gerstner Sloan Kettering Graduate School of Biomedical Sciences
      Offering a curriculum with a focus on cancer
    - PhD & MD/PhD programs
    - MSK Bridge program
      Connecting college seniors to future careers in biomedicine
    - High school & undergraduate summer programs
- Careers
- MSK Direct
- - - In the U.S.
    - English
    - Español
    - Pу́сский
    - Outside of the U.S.
    - العَرَبِيَّة
    - Deutsch
    - English
    - Español
    - 한국어
    - עִבְרִית
    - Italiano
    - Português
    - Pу́сский
    - Türkçe
    - 中文

Jessica Rios-Esteves, PhD

Technical Program Lead, Legend Biotech, Piscataway, NJ

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Dissertation

Fatty Acylation of WNT Proteins by the Acyltranferase Porcupine (2014)

Mentor

Marilyn Resh, PhD

End Year

2014

Education

University of Puerto Rico at Mayagüez

Publications

Rios-Esteves J, Haugen B, Res M. (2014) Identification of Key Residues and Regions Important for Porcupine-mediated Wnt Acylation. J Biol Chem, 289, 17009-17019. PMCID: PMC4059143.

Petrova E, Rios-Esteves J, Ouerfelli O, Glickman J, Resh M. (2013) Inhibitors of Hedgehog acyltransferase block Sonic Hedgehog signaling. Nat Chem Biol, 9, 247-249. PMCID: PMC3604071.

Rios-Esteves J, Resh M. (2013) Stearoyl CoA desaturase is required to produce active, lipid-modified Wnt proteins. Cell Rep, 4, 1072-1081. PMCID: PMC3845236.

Changing how the world understands and treats cancer

Training the next generation of clinicians and scientists

Jessica Rios-Esteves, PhD

Technical Program Lead, Legend Biotech, Piscataway, NJ

Jessica Rios-Esteves, PhD

Technical Program Lead, Legend Biotech, Piscataway, NJ

Dissertation

Mentor

End Year

Education

Publications