Leili Ran

Graduate Research Technician

Email

ranl@sloankettering.edu

Mentor

Ping Chi

Start Year

2011

Education

BS, Tsinghua University

To state it simply: I want to understand more about the world. I want to help cure cancer. And science makes that possible. It allows me to explore the unknown and solve problems. Pursing my PhD gives me the flexibility to determine if I want to become a professor in the future. But whether I take that path or another, graduate work at Gerstner Sloan Kettering has offered me the opportunity to study at the best cancer institute in the world, and the benefits of such a collaborative environment will resonate if I continue in cancer medicine research or not.

Publications

Wiesner T, Lee W, Obenauf AC, Ran L, Murali R, Zhang QF et al. (2015) Alternative transcription initiation leads to expression of a novel ALK isoform in cancer. Nature. 526, 453-7.

Ran L, Sirota I, Cao Z, Murphy D, Chen Y, Shukla S et al. (2015) Combined inhibition of MAP kinase and KIT signaling synergistically destabilizes ETV1 and suppresses GIST tumor growth. Cancer Discov. 5, 304-15.

Gao D, Vela I, Sboner A, Iaquinta PJ, Karthaus WR, Gopalan A, Dowling C, et al. (2014)  Organoid cultures derived from patients with advanced prostate cancer. Cell. 159, 176-87.

Sheth A, Escobar-Alvarez S, Gardner J, Ran L, Heaney ML, Scheinberg DA. (2014) Inhibition of human mitochondrial peptide deformylase causes apoptosis in c-myc-overexpressing hematopoietic cancers.  Cell Death Dis. 5, e1152.

Lee W, Teckie S, Wiesner T, Ran L, Prieto Granada CN, et al. (2014)_ PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors. Nat Genet. 46, 1227-32.

Yi C, Ma M, Ran L, Zheng J, Tong J, Zhu J, et al. (2012) Function and molecular mechanism of acetylation in autophagy regulation. Science. 336, 474-7.