Human Oncology & Pathogenesis Program

The Ross Levine Lab

Research

Pictured: Dr. Ross Levine
Ross L. Levine, MD

The goal of our research is to improve our understanding of the genetic basis of blood disorders known as myeloid malignancies, and to use this knowledge to improve therapies for patients with these disorders. Our efforts are focused on the identification and characterization of somatic mutations in hematologic malignancies using candidate gene, genome-wide, and functional approaches, with a specific interest in the role of aberrant signal transduction in malignant transformation and in the effects of mutations in epigenetic modifiers in myeloproliferative neoplasms (MPNs) and acute myeloid leukemia (AML). As a physician-scientist, we have a specific interest in translating this knowledge back to the clinic, in the preclinical and clinical evaluation of targeted therapies for leukemia patients, and in the development of clinically tractable genomic assays for patients with hematologic malignancies.

The Levine Lab

The Levine Lab

Publications

People

Pictured: Dr. Ross Levine

Ross L. Levine, MD

  • Mechanisms of genetic and epigenetic cooperativity  which drive myeloid transformation
  • Elucidating and modeling evolution from hematopoietic stem/progenitor cells to clonal hematopoiesis and then to myeloid malignancies
  • Identification and credentialing novel therapeutic dependencies in myeloid malignancies
  • MD, Johns Hopkins School of Medicine
leviner@mskcc.org
Email Address
View physician profile
Physician profile

Members

Robert Bowman
Robert Bowman

Postdoctoral Fellow

Stephanie Braunstein
Stephanie Braunstein

Senior Research Technician

Sheng Cai, MD, PhD
Sheng Cai

Instructor, Department of Medicine

Christine Caprioli
Christine Caprioli

Program Assistant

Isabelle Csete
Isabelle Csete

Research Technician

Nicole DelGaudio
Nicole DelGaudio

Research Technician

Andrew Dunbar, MD
Andrew Dunbar

Instructor, Department of Leukemia

Jacob Glass
Jacob Glass

Research Fellow

Abdul Karzai

Senior Research Technician

Aishwarya Krishnan

Research Technician

Aishwarya Krishnan
Aishwarya Krishnan

Senior Research Technician

Bing Li

Visiting Investigator

Ines Maestre

GSK Graduate Student

Linde Miles
Linde Miles

Postdoctoral Research Fellow

Tanmay Mishra

Senior Research Technician

Shoron Mowla
Shoron Mowla

Research Technician

Young Park
Young Park

Senior Research Technician

Raajit K. Rampal, MD, PhD
Raajit K. Rampal

Assistant Attending

Troy Robinson
Troy Robinson

GSK Graduate Student

Aaron Stonestrom

Fellow

Pablo Sánchez Vela, MD
Pablo Sánchez Vela

Research Scholar

Pictured: Aaron Viny
Aaron Viny

Assistant Attending

Karen Wei
Karen Wei

Lab Manager

Anouar Zouak

Research Technician

Lab Alumni
Nicole Kucine, MD
Nicole Kucine
Sachie Marubayashi
Sachie Marubayashi

Research Technician

Alison Schram, BS
Alison Schram

Graduate Research Assistant

Jihae Ahn
Jihae Ahn

Research Technician

Lennart Bastian
Lennart Bastian

Research Technician

Neha Bhagwat
Neha Bhagwat

Senior Research Scientist at Prelude Therapeutics Inc., Wilmington, Delaware

Sophia Chiu, MS
Sophia Chiu

Research Technician

Young Rock Chung

Research Technician

Keith Cordner

Research Technician

Lauren Dong

Research Technician

Vidushi Durani

Research Technician

Olga Guryanova
Olga Guryanova

Research Fellow

Megan Hatlen
Megan Hatlen

Research Fellow

Todd Hricik
Todd Hricik

Research Assistant

Matthew Keller
Matthew Keller

Research Technician

Outi Kilpivaara

Research Fellow

Maria Kleppe

Research Fellow

Priya Koppikar, PhD
Priya Koppikar

Research Fellow

Hiroyoshi Kunimoto, MD, PhD
Hiroyoshi Kunimoto

Research Fellow

Lindsay M. Saunders, BS
Lindsay M. LaFave (Saunders)

Research Fellow

Anna Sophia McKenney
Anna Sophia McKenney

Interventional Radiology Resident at New York Presbyterian Hospital, New York, NY

Tiffany Merlinsky
Tiffany Merlinsky

NE Agency Contingent

Sara Meyer
Sara Meyer

Research Fellow

Christine Mullane
Christine Mullane

Administrative Assistant

Abbas Nazir

Research Technician

Suveg Pandey, BS
Suveg Pandey

Research Technician

Efi Papalexi
Efi Papalexi

Research Technician

Friederike Pastore, MD
Friederike Pastore

Research Fellow

Jay Patel

Research Trainee

Elodie Pronier

Research Fellow

Franck Rapaport
Franck Rapaport

Senior Research Scientist

Shira Redlich
Shira Redlich

Senior Research Technician

Kaitlyn Shank
Kaitlyn Shank

Research Technician

Alan Shih, MD, PhD
Alan Shih

Assistant Attending

Amritha Hanasoqe Somasundara

Research Technician

B. Gila Spitzer
B. Gila Spitzer

Instructor, Department of Pediatrics

Brittany A. Woods, BS
Brittany A. Woods

Graduate Student

Lab Affilations

Achievements

  • Scholar, Leukemia and Lymphoma Society Scholar (2012)
  • Louis and Allston Boyer Young Investigator Award for Basic Research, Memorial Sloan Kettering Cancer Center (2011)
  • Member, American Society of Clinical Investigation (2011)
  • Sir William Osler Young Investigator Award, Interurban Clinical Club (2011)

Get in Touch

Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Ross L. Levine discloses the following relationships and financial interests:

  • Ajax Therapeutics, Inc.
    Intellectual Property Rights; Ownership / Equity Interests
  • Astra Zeneca
    Provision of Services
  • Auron Therapeutics, Inc.
    Ownership / Equity Interests; Provision of Services (uncompensated)
  • C4 Therapeutics
    Ownership / Equity Interests; Provision of Services
  • Celgene
    Provision of Services
  • Constellation Pharmaceuticals
    Provision of Services
  • Cure Breast Cancer Foundation
    Intellectual Property Rights
  • ECOG-ACRIN Cancer Research Group
    Provision of Services (uncompensated)
  • Epizyme
    Intellectual Property Rights
  • Fulcrum 2020, LLC
    Provision of Services
  • Genome Quebec
    Provision of Services
  • Gilead Pharmaceutical
    Provision of Services
  • Imago Biosciences
    Ownership / Equity Interests; Provision of Services
  • Incyte
    Provision of Services
  • Isoplexis Corporation
    Ownership / Equity Interests; Provision of Services
  • Janssen Pharmaceuticals, Inc.
    Provision of Services
  • Jubilant Therapeutics Inc.
    Provision of Services
  • K-Group
    Ownership / Equity Interests
  • Lilly Oncology
    Provision of Services
  • Loxo Oncology
    Ownership / Equity Interests
  • Mana Therapeutics, Inc.
    Provision of Services
  • Moderna, Inc.
    Provision of Services (uncompensated)
  • Prelude Therapeutics
    Provision of Services (uncompensated)
  • Qiagen
    Fiduciary Role/Position; Ownership / Equity Interests
  • The Mark Foundation
    Fiduciary Role/Position; Provision of Services
  • University of Helsinki
    Provision of Services
  • VIB-KU Leuven Center for Cancer Biology
    Provision of Services
  • Zentalis Pharmaceuticals
    Ownership / Equity Interests

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.


This page and data include information for a specific MSK annual disclosure period (January 1, 2019 through disclosure submission in spring 2020). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at ecoi@mskcc.org.


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