Human Oncology & Pathogenesis Program
The Ross Levine Lab
Research

The goal of our research is to improve our understanding of the genetic basis of blood disorders known as myeloid malignancies, and to use this knowledge to improve therapies for patients with these disorders. Our efforts are focused on the identification and characterization of somatic mutations in hematologic malignancies using candidate gene, genome-wide, and functional approaches, with a specific interest in the role of aberrant signal transduction in malignant transformation and in the effects of mutations in epigenetic modifiers in myeloproliferative neoplasms (MPNs) and acute myeloid leukemia (AML). As a physician-scientist, we have a specific interest in translating this knowledge back to the clinic, in the preclinical and clinical evaluation of targeted therapies for leukemia patients, and in the development of clinically tractable genomic assays for patients with hematologic malignancies.

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Publications Highlights
People

Ross L. Levine, MD
Senior Vice President, Memorial Hospital, Translational Research
- Mechanisms of genetic and epigenetic cooperativity which drive myeloid transformation; Elucidating and modeling evolution from hematopoietic stem/progenitor cells to clonal hematopoiesis and then to myeloid malignancies; Identification and credentialing novel therapeutic dependencies in myeloid malignancies
- MD, Johns Hopkins School of Medicine
- [email protected]
- Email Address
- View physician profile
- Physician profile
Members






- BS, Universitat Autonoma de Barcelona
- MS, Fachhochschule Technikum Wien
- Cancer Biology

- BA, University of Pennsylvania
- MS, University of Pennsylvania
- Cancer Biology








Research Technician

Assistant Attending

Research Lab Manager

Project Coordinator

NE Student affiliated
Research Scholar

Postdoctoral Fellow, Cold Spring Harbor Laboratory

GSK Graduate Student

Senior Research Assistant

Senior Research Technician
Research Technician
Research Technician

Research Technician

Associate Attending

GSK Graduate Student
Data Scientist II

Senior Research Scientist

Research Assistant

Instructor
Associate Attending


- Drexel University

- Vanderbilt University











- University of Michigan
- 646-888-2796
- Lab Phone

- Rensselaer Polytechnic University
- 646-888-2796
- Lab Phone










- BS, Boston College
Lab Alumni


Research Technician

Graduate Research Assistant

Research Technician

Research Technician
Lab Technician

Associate Director, Translational Medicine at Prelude Therapeutics Inc., Wilmington, Delaware

Assistant Professor, University of Pennsylvania, Philadelphia, PA

Senior Research Technician

Research Technician

Research Technician
Research Technician
Research Technician

Research Technician

Research Technician
Research Technician

Instructor, Department of Leukemia
Research Technician

Research Fellow
Lab Technician

Research Fellow

Research Technician

Research Assistant
Senior Research Technician

Research Technician
Research Fellow
Research Fellow

Research Fellow

Senior Research Technician

Research Fellow

Research Fellow
Visiting Investigator

Interventional Radiology Resident at New York Presbyterian Hospital, New York, NY

NE Agency Contingent

Research Fellow

Assistant Professor, University of Cincinnati
Senior Research Technician

Research Technician

Administrative Assistant
Research Technician
Research Technician
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Research Technician

Research Technician

Senior Research Technician

Research Fellow
Research Trainee

Research Technician

Research Fellow

Senior Research Scientist

Senior Research Technician
Research Technician

Research Technician

Assistant Attending

Postdoctoral Fellow
Research Technician
Fellow

Assistant Attending
GSK Graduate Student

Lab Manager

Equity Research Associate at William Blair Cowen, Inc., New York, NY
Research Technician
Research Technician
Lab Affiliations
Achievements
- Scholar, Leukemia and Lymphoma Society Scholar (2012)
- Louis and Allston Boyer Young Investigator Award for Basic Research, Memorial Sloan Kettering Cancer Center (2011)
- Member, American Society of Clinical Investigation (2011)
- Sir William Osler Young Investigator Award, Interurban Clinical Club (2011)
Open Positions
To learn more about available postdoctoral opportunities, please visit our Career Center
To learn more about compensation and benefits for postdoctoral researchers at MSK, please visit Resources for Postdocs
Get in Touch
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Lab Head Email
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Lab Phone
Disclosures
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Ross L. Levine discloses the following relationships and financial interests:
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Ajax Therapeutics, Inc.
Equity; Fiduciary Role / Position; Intellectual Property Rights; Professional Services and Activities (Uncompensated) -
Anovia Biosciences, Inc
Equity -
Auron Therapeutics, Inc.
Equity; Professional Services and Activities (Uncompensated) -
Bakx Therapeutics
Equity -
C4 Therapeutics
Equity; Professional Services and Activities -
Cure Breast Cancer Foundation
Intellectual Property Rights -
ECOG-ACRIN Cancer Research Group
Professional Services and Activities (Uncompensated) -
Epiphanes, Inc.
Equity -
Epizyme
Intellectual Property Rights -
Genome Quebec
Professional Services and Activities -
Goldman Sachs
Professional Services and Activities
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Isoplexis Corporation
Equity; Professional Services and Activities (Uncompensated) -
Jubilant Therapeutics Inc.
Professional Services and Activities -
Kurome Therapeutics, Inc.
Equity; Professional Services and Activities -
Mission Bio
Equity; Professional Services and Activities -
Prelude Therapeutics
Equity; Professional Services and Activities (Uncompensated) -
Qiagen
Equity; Fiduciary Role / Position; Professional Services and Activities (Uncompensated) -
Scorpion Therapeutics, Inc.
Equity; Professional Services and Activities -
Syndax
Equity -
The Mark Foundation
Fiduciary Role / Position; Professional Services and Activities -
Zentalis Pharmaceuticals
Equity; Professional Services and Activities (Uncompensated)
The information published here is a complement to other publicly reported data and is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.
This page and data include information for a specific MSK annual disclosure period (January 1, 2023 through disclosure submission in spring 2024). This data reflects interests that may or may not still exist. This data is updated annually.
Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].