Human Oncology & Pathogenesis Program
The Ross Levine Lab
Research
The goal of our research is to improve our understanding of the genetic basis of blood disorders known as myeloid malignancies, and to use this knowledge to improve therapies for patients with these disorders. Our efforts are focused on the identification and characterization of somatic mutations in hematologic malignancies using candidate gene, genome-wide, and functional approaches, with a specific interest in the role of aberrant signal transduction in malignant transformation and in the effects of mutations in epigenetic modifiers in myeloproliferative neoplasms (MPNs) and acute myeloid leukemia (AML). As a physician-scientist, we have a specific interest in translating this knowledge back to the clinic, in the preclinical and clinical evaluation of targeted therapies for leukemia patients, and in the development of clinically tractable genomic assays for patients with hematologic malignancies.
The Levine Lab
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People
Ross L. Levine, MD
- Mechanisms of genetic and epigenetic cooperativity which drive myeloid transformation; Elucidating and modeling evolution from hematopoietic stem/progenitor cells to clonal hematopoiesis and then to myeloid malignancies; Identification and credentialing novel therapeutic dependencies in myeloid malignancies
- MD, Johns Hopkins School of Medicine
- [email protected]
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Members
Lab Technician
Postdoctoral Fellow
Research Technician
Instructor, Department of Medicine
Project Coordinator
Instructor, Department of Leukemia
GSK Graduate Student
GSK Graduate Student
Research Fellow
Lab Technician
Research Technician
Visiting Investigator
Postdoctoral Research Fellow
Research Technician
Senior Research Technician
Research Technician
Assistant Attending
GSK Graduate Student
Postdoctoral Fellow
Fellow
Research Scholar
GSK Graduate Student
Senior Research Technician
Fellow
Assistant Attending
Lab Alumni
Research Technician
Graduate Research Assistant
Research Technician
Research Technician
Associate Director, Translational Medicine at Prelude Therapeutics Inc., Wilmington, Delaware
Senior Research Technician
Research Technician
Research Technician
Research Technician
Research Technician
Research Technician
Research Technician
Research Technician
Research Fellow
Research Fellow
Research Assistant
Senior Research Technician
Research Technician
Research Fellow
Research Fellow
Research Fellow
Senior Research Technician
Research Fellow
Research Fellow
Interventional Radiology Resident at New York Presbyterian Hospital, New York, NY
NE Agency Contingent
Research Fellow
Senior Research Technician
Administrative Assistant
Research Technician
Research Technician
Research Technician
Research Fellow
Research Trainee
Research Fellow
Senior Research Scientist
Senior Research Technician
Research Technician
Assistant Attending
Research Technician
Instructor, Department of Pediatrics
Assistant Attending
Lab Manager
Equity Research Associate at William Blair Cowen, Inc., New York, NY
Research Technician
Lab Affiliations
Achievements
- Scholar, Leukemia and Lymphoma Society Scholar (2012)
- Louis and Allston Boyer Young Investigator Award for Basic Research, Memorial Sloan Kettering Cancer Center (2011)
- Member, American Society of Clinical Investigation (2011)
- Sir William Osler Young Investigator Award, Interurban Clinical Club (2011)