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Research Lab
Physician-scientist Katharine Hsu studies the biology of human natural killer cells and how they contribute to disease processes.
… My laboratory studies the natural killer (NK) cell and the molecules that control its ability to recognize and kill cancer and virally infected cells. Improved understanding of how NK cells behave is critical to advancing our ability to harness their innate capacity for tumor recognition and eradication
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Research Lab
Physician-scientist Rachel Niec studies how cells and tissues communicate to promote health or drive inflammation and cancer.
… Complex tissue functions, such as nutrient absorption and barrier defense in the intestine, are influenced and tuned by environmental cues and stresses. However, the environmentally tuned cellular interaction networks that define tissue health and resilience or predispose to disease states are poorly
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Research Lab
… The Kung Lab leverages patient-driven discovery to identify drivers and therapeutic vulnerabilities in pediatric and young adult cancers. The research infrastructure of the lab bridges the clinic, dry lab, and wet lab, with experimental data derived from model systems as well as in-human studies. We
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Research Lab
Kenneth Marians focuses on mechanisms of replication restart and chromosome segregation.
… Research in my laboratory centers on: (i) the events that occur when the replisome (the multi-component enzyme machine that replicates chromosomal DNA) encounters blockages to replication fork progression, and (ii) the mechanisms by which chromosomes are condensed and separated during cell division.
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Research Lab
The Gitlin Lab studies the molecular and cellular mechanisms underlying inflammatory cell signaling in health and disease.
… The Alexander Gitlin Lab studies how inflammatory cell signaling controls the nature and magnitude of inflammation under physiological and disease conditions. Innate immune cells are tasked with integrating diverse molecular signals from both host and pathogen to produce appropriately commensurate inflammatory
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Research Lab
My laboratory and clinical research focus on understanding genomics and signaling in colorectal cancer to develop new treatments for patients.
… My laboratory and clinical research focus on understanding genomics and signaling in colorectal cancer to develop new treatments for patients. Colorectal tumors are characterized by a high level of baseline receptor tyrosine kinase (RTK) signaling. Oncogenic inhibition of these tumors, for example with
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Research Lab
Physician-scientist Prasad S. Adusumilli studies tumor immunology and the development of T-cell‒mediated immunotherapy for thoracic malignancies and pleural-based diseases.
… Research led by Prasad S. Adusumilli focuses on investigation of the tumor immune microenvironment and the development of T-cell‒mediated immunotherapy for thoracic malignancies and pleural-based diseases. His team has championed regional immunotherapy delivery strategies, resulting in translation of
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Research Lab
Associate Attending Computer Scientist Harini Veeraraghavan's lab develops and translates new AI and machine learning tools diagnosing and personalizing cancer treatments through automated segmentation of normal tissues and tumors applied to radiation treatment automation, early predicting treatment response and toxicity prediction, and longitudinal tumor treatment response monitoring from medical images.
… Associate Attending Computer Scientist Harini Veeraraghavan’s lab develops and translates new AI and machine learning tools diagnosing and personalizing cancer treatments through automated segmentation of normal tissues and tumors applied to radiation treatment automation, early predicting treatment
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Research Lab
Dr. Ahmet Dogan is a board-certified pathologist and an internationally recognized leader in hematopathology. His current research interests include lymphoma, plasma cell disorders, and diagnostic techniques for hematopathology such as cytogenetic analysis, genomics, and proteomics. His previous work has contributed much to the understanding of the histogenesis of lymphomas, MALT lymphomas, and T cell lymphomas in particular.
… The Ahmet Dogan lab within the Hematopathology Service establishes new diagnostic approaches and diagnostic test utilization algorithms, which will determine the standard of care for the hematopathology practice. The Service catalogues and analyzes the pathological features of hematological malignancies
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Research Lab
The Gabrielle Rizzuto lab investigates a long-standing question in immunology: what prevents maternal immune rejection of the placenta and fetus?
… The Gabrielle Rizzuto lab investigates a long-standing question in immunology: what prevents maternal immune rejection of the placenta and fetus? The immune system must be able to discriminate self from non-self. Pregnancy is a beautiful exception to the paradigm that non-self is immunogenic, since the