A Study Assessing a Lower Dose of Radiation Therapy after Surgery for Soft Tissue Sarcoma of the Arms and Legs


Full Title

Reduction of Dose and Volume in Postoperative Radiation for Extremity Soft Tissue Sarcoma


Radiation therapy after surgery is standard care for soft tissue sarcoma of the arms and legs. In this study, researchers want to find out if lowering the dose of radiation therapy by 20 percent and targeting a smaller, more focused area of tissue is as effective as the standard dose and volume for treating soft tissue sarcoma after surgery.

The lower dose of radiation used in this study is the same dose used when people with sarcoma have radiation before surgery. The study investigators also want to see if a lower radiation dose results in fewer long-term side effects.

Who Can Join

To be eligible for this study, patients must meet several criteria, including but not limited to the following:

  • Patients must have soft tissue sarcoma of the arm or leg that can be surgically removed.
  • Patients should be able to start radiation therapy within three months of surgery.
  • This study is for patients age 18 and older.

For more information about this study and to inquire about eligibility, please contact Dr. Kaled Alektiar at 212-639-7981.




Phase II (phase 2)



ClinicalTrials.gov ID