A Phase II Study of ZEN003694 in People with Advanced Squamous Cell Lung Cancer

Full Title

Phase 2 trial of ZEN003694 in Squamous Cell Lung Cancer Patients Harboring NSD3 Amplification

Purpose

The purpose of this study is to assess the safety and effectiveness of the investigational drug ZEN003694 in people with advanced squamous cell lung cancer that continues to grow despite treatment and contains multiple copies of a gene called NSD3. ZEN003694 blocks a group of proteins called BET, which may counteract the effect of NSD3 on tumor growth. Blocking these proteins may slow or stop the growth of lung cancer. ZEN003694 is taken orally (by mouth).

Contact

For more information about this study and to ask about eligibility, please contact the office of Dr. Paul Paik at 646-608-3759.