A Study of Radiotherapy and Pembrolizumab in People With Adrenocortical Carcinoma

Full Title

Safety and Immunological Effects of Pembrolizumab Plus Ablative Radiotherapy in Patients with Advanced Adrenocortical Carcinoma

Purpose

Researchers want to see if combining radiation therapy and immunotherapy is safe and works well for treating advanced adrenocortical cancer. The people in this study have adrenocortical cancer that spread to other parts of the body, including the liver.

If you join this study, you will first have a type of radiation called intensity-modulated radiation therapy (IMRT). IMRT directs radiation to cancer cells from different angles by changing the radiation beam into multiple smaller beams.

Then you will get pembrolizumab. This drug takes the brakes off the immune response, allowing your immune system to find and kill cancer cells. It is given intravenously (by vein).

Contact

For more information or to see if you can join this study, please call Dr. Nitya Raj’s office at 646-888-4849.