At any time Memorial Sloan Kettering Cancer Center is conducting hundreds of clinical trials to improve care for many types of cancer. Use the tool below to browse our clinical trials that are currently enrolling new patients. Each listing explains the purpose of the trial, the trial’s eligibility criteria, and how to get more information.
The list below includes clinical trials for adult cancers. Please visit our pediatric cancer care section to find a pediatric clinical trial.
Memorial Sloan Kettering offers language assistance services for those who prefer to receive health information in another language. Learn more about our language assistance program here.
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The purpose of this study is to assess the feasibility of a new approach to treat people with T4 breast cancer who have already received chemotherapy. T4 breast cancer occurs when the cancer has grown beyond normal breast tissue and into the chest wall or skin or has become swollen and causes pain. Doctors normally treat T4 breast cancer with chemotherapy followed by mastectomy and removal of underarm (axillary) lymph nodes. After mastectomy, patients normally receive radiation therapy and then have breast reconstruction surgery many months to years after completing radiotherapy.
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Researchers want to find the best dose of 225Ac-ABD147 to treat advanced lung cancer. The people in this study have small cell lung cancer (SCLC) or large cell neuroendocrine carcinoma of the lung (LCNEC). Their cancer keeps growing even after treatment that included platinum-based chemotherapy.
- A Study Comparing Music Therapy and Cognitive Behavioral Therapy for Anxiety in Cancer Survivors
Full Title Music Therapy vs. Cognitive-Behavioral Therapy for Cancer-related Anxiety (MELODY)
Purpose
Many cancer survivors suffer from anxiety. Anxiety may involve feelings of restlessness, muscle tension, and worry. Anxiety has also been linked to poor sleep, depressed mood, and tiredness. Researchers are doing this study to see how music therapy and cognitive behavioral therapy may be able to reduce anxiety and these other symptoms. Both music therapy and cognitive behavioral therapy are routinely used to treat anxiety.
Cognitive behavioral therapy is based on the idea that thoughts, feelings, and actions are all connected. It is a type of talk therapy (therapy focusing on conversations between a patient and healthcare provider) that helps a person change their thought patterns and behavior. Music therapy uses music to encourage healing and promote a sense of well-being. It can include listening to music to help relax and making music by singing or writing a song.
In this study, the music therapy and cognitive behavioral therapy sessions will be virtual, meaning that they will take place online rather than in person. Participants will be randomly assigned to receive one type of therapy or the other, but not both.
Who Can Join
To be eligible for this study, patients must meet several requirements, including:
- Participants must have completed cancer treatment at least one month before entering the study. They must also be experiencing anxiety or worry lasting at least one month.
- Patients must have no evidence of cancer.
- Patients must speak English or Spanish.
- This study is for people age 18 and older.
For more information about this study, please contact the Clinical Research Coordinator at 646-449-1028 or email [email protected].
Protocol
21-516Phase
Phase IV (phase 4)Investigator
Co-Investigators
Locations
ClinicalTrials.gov ID
NCT05215353ClinicalTrials.gov
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BV-AVD is a combination of drugs used to treat advanced (stage 3 or 4) Hodgkin lymphoma. Researchers in this study want to see how well it works to treat early-stage bulky Hodgkin lymphoma. The people in this study have stage 1 or 2 bulky Hodgkin lymphoma that has not yet been treated.
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Researchers are comparing taletrectinib with a placebo (inactive drug) in people with non-small cell lung cancer (NSCLC). The people in this study have stage 1B-3A NSCLC that has a ROS1 gene fusion. They have had the tumor completely removed with surgery.
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The purpose of this study is to see if one year of treatment with olaparib is better than observation alone in patients who had pancreatic cancer surgically removed and who have mutations in the BRCA1, BRCA2 or PALB2 genes. Olaparib is a type of anticancer medication called a PARP inhibitor, which may slow down the process cancer cells use to repair their DNA. Cancer cells need to repair their DNA to survive and grow.
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Limited metastatic colorectal cancer is cancer that has spread to no more than 4 parts of the body. The usual treatment for limited metastatic colorectal cancer is chemotherapy. In this study, researchers want to see if adding local therapies makes treatment work better. Local therapies are used to treat cancer only at specific sites.
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To learn more about the purpose of this study and to find out who can join, please click here to visit ClinicalTrials.gov for a full clinical trial description.
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The purpose of this study is to find the highest dose of the drug alectinib that can be given safely in children and adolescents with solid tumors or brain and spinal cord cancers that persist after treatment and have a genetic change called an ALK gene fusion. With this gene fusion, the ALK gene attaches to part of another gene.
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Researchers are assessing Lutetium-FAP for people with advanced pancreatic cancer. Lutetium-FAP is a drug with a radioactive part attached. It targets cancer cells that make a protein called FAP, which may help cancer grow and survive. Lutetium-FAP combines a radiation-emitting metal with a tumor-targeting agent to deliver radiation into a tumor and destroy cancer cells.