At any time Memorial Sloan Kettering Cancer Center is conducting hundreds of clinical trials to improve care for many types of cancer. Use the tool below to browse our clinical trials that are currently enrolling new patients. Each listing explains the purpose of the trial, the trial’s eligibility criteria, and how to get more information.
The list below includes clinical trials for adult cancers. Please visit our pediatric cancer care section to find a pediatric clinical trial.
Memorial Sloan Kettering offers language assistance services for those who prefer to receive health information in another language. Learn more about our language assistance program here.
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Researchers want to find the best dose of INCB160058 to treat myeloproliferative neoplasms such as myelofibrosis. The people in this study have myeloproliferative neoplasms that came back or keep growing even after treatment. In addition, their cancers have a mutation (change) in the JAK2 gene.
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Studies have shown that patients with newly diagnosed localized non-germinomatous germ cell tumors (NGGCT) of the brain or spinal cord whose disease responds well to chemotherapy before receiving radiation therapy are more likely to be free of the disease for a longer time than patients in whom chemotherapy is less effective.
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The purpose of this study is to assess the safety and effectiveness of a specialized light treatment for children and adults with chronic graft-versus host disease (GVHD) of the mouth (oral GVHD) that has not improved after standard treatment. GVHD is a complication that can occur after a stem cell or bone marrow transplant. The newly transplanted donor cells attack the transplant recipient's body and cause serious health problems. Oral GVHD can cause mouth inflammation, pain, and sores.
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Researchers are assessing a lower dose of standard radiation therapy after chemotherapy in young people with germinomas. The patients in this study have germinomas of the central nervous system (brain or spinal cord).  It is hoped that this new approach can destroy germinomas with fewer long-term side effects.
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Researchers in this study are seeking the best dose of CBL0137 in people with solid tumors. They also want to see how well it works against certain cancers.
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To learn more about the purpose of this study and to find out who can join, please click here to visit ClinicalTrials.gov for a full clinical trial description.
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Researchers want to see if elacestrant alone or with abemaciclib works well against endometrial cancer. The people in this study have endometrial cancer that has spread or come back. Their cancers have a protein called the estrogen receptor (ER) and they have a normal version of the p53 gene. This gene stops cancer from growing.
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Ruxolitinib is used to treat myelofibrosis, a rare bone marrow cancer that disrupts your body's normal blood cell production. Some people taking this drug, however, keep having symptoms. Researchers want to see if adding the drug ulixertinib to ruxolitinib treatment is safe and works better to treat myelofibrosis.
- A Study of Acupuncture for Young Adults Who Stopped Getting Periods After Chemotherapy
Full Title Acupuncture for Adolescent and Young Adult Cancer Patients: (AcuAYA)
Purpose
Many people who get chemotherapy experience a loss of their period (amenorrhea). They may have menopause-like symptoms such as insomnia, hot flashes, and anxiety. The condition also increases the risk of infertility.
There is no treatment for period loss in people getting chemotherapy for cancer. Researchers are assessing acupuncture to treat amenorrhea caused by chemotherapy in young adults with cancer.
Acupuncture is a medical technique that involves the insertion of very thin needles into specific areas on the body. The goal is to promote health and well-being. Studies have shown that acupuncture may help recover the function of the ovaries and balance sex hormone levels.
If you join this study, you will be randomly assigned to one of these groups:
- The acupuncture group, who will have 12 acupuncture treatments over 12 weeks.
- The control group, who will be put on a waitlist. They will be able to have the same acupuncture treatment as the acupuncture group after a 16-week waiting period.
Who Can Join
To join this study, there are a few conditions. You must:
- Be English-speaking and under age 40.
- Had stage 1, 2, or 3 cancer diagnosed between the ages of 18 and 39.
- Had been having regular periods at the time of your cancer diagnosis.
- Have completed chemotherapy within the past year.
- Have not had a period for at least 3 months after finishing chemotherapy.
Contact
For more information about this study, please contact the Clinical Research Coordinator at [email protected] or 646-449-1074.
Protocol
25-020Phase
Phase II (phase 2)Investigator
Co-Investigators
Xiaotong LiDiseases
Locations
ClinicalTrials.gov ID
NCT06915116ClinicalTrials.gov
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Researchers are assessing petosemtamab given alone or with standard chemotherapy in people with advanced colorectal cancer. The people in this study have colorectal cancer that is inoperable (cannot be removed with surgery) or has metastasized (spread).