Esophageal Cancer Clinical Trials & Research

Researchers at Memorial Sloan Kettering are studying new approaches to esophageal cancer, and we come closer to finding exciting solutions every day. One of the most important goals we have is to develop better treatments for people with esophageal cancer who are not helped by standard treatments.

We lead clinical trials to make current treatments better and to enhance the quality of life for people with esophageal cancer. Eligible patients may get experimental treatments before they are widely available elsewhere.

Memorial Sloan Kettering’s clinical trials for esophageal cancer are listed below. There may be other trials that are right for your cancer. Consult with your physician, who can ask if a trial is right for you.

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27 Clinical Trials found
A Phase IB/II Study of Trastuzumab Deruxtecan in People with Advanced Gastric Cancer or Gastroesophageal Junction Cancer
Trastuzumab is an anticancer medication that targets HER2, a protein overproduced by some cancers of the stomach (gastric cancers) and the junction between the stomach and esophagus (gastro-esophageal junction or GEJ cancers). In this study, researchers are evaluating the safety of combining the drug trastuzumab deruxtecan (T-DXd) with immunotherapy and/or chemotherapy in patients with inoperable or metastatic stomach and GEJ cancers that have come back or continued to grow despite prior treatment.
New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau
A Phase III Study Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer
The purpose of this study is to compare proton beam radiation therapy with intensity-modulated radiation therapy (IMRT) in patients with stage I-IVA esophageal cancer. Both approaches send radiation inside the body to a tumor without damaging much of the healthy tissue around it. However, proton beam radiation therapy uses protons while IMRT uses photons (high-energy x-rays).
New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau
A Study of BNT329 in People With Solid Tumors
To learn more about the purpose of this study and to find out who can join, please click here to visit ClinicalTrials.gov for a full clinical trial description.
New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau
A Study of Drug Combinations Before and After Surgery in People With Gastric, Esophageal, and Gastroesophageal Junction (GEJ) Cancer
To learn more about the purpose of this study and to find out who can join, please click here to visit ClinicalTrials.gov for a full clinical trial description.
New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau
A Study of EVOLVE104 in People With Solid Tumor Cancer
To learn more about the purpose of this study and to find out who can join, please click here to visit ClinicalTrials.gov for a full clinical trial description.
New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau
A Study of Pumitamig and Chemotherapy Versus Nivolumab and Chemotherapy in People With Gastric, Gastroesophageal Junction (GEJ), or Esophageal Cancer
To learn more about the purpose of this study and to find out who can join, please click here to visit ClinicalTrials.gov for a full clinical trial description.
New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau
A Study of Telisotuzumab Adizutecan (ABBV-400) in People With Solid Tumor Cancer
To learn more about the purpose of this study and to find out who can join, please click here to visit ClinicalTrials.gov for a full clinical trial description.
New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau