Mesothelioma Clinical Trials & Research

Because we’re involved in research related to all aspects of care, Memorial Sloan Kettering is often the first to be aware of the latest scientific discoveries and medical advances for mesothelioma. We’re constantly testing new ways to fight mesothelioma. Our patients have access to clinical trials of new treatment options that are not available in most other hospitals.

As a mesothelioma patient at Memorial Sloan Kettering — regardless of the stage of your disease — there will likely be a clinical trial option for you.

These research studies evaluate the safety and effectiveness of new ways to diagnose and treat mesothelioma. They can also give your treatment team information about your current plan of care. Promising approaches that we’ve looked at so far include tumor vaccines, antibody therapies, T cell–based treatments, molecularly targeted medications, and the use of anticancer viruses.

Here you can find a continually updated listing of MSK’s current clinical trials for mesothelioma. To learn more about a study, choose from the list below.

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5 Clinical Trials found
A Phase 1 Study of VT3989 in People With Mesothelioma
Researchers are assessing the safety of the drug VT3989 in people with mesothelioma. The people in this study have mesothelioma with a mutation (change or variant) in the NF2 gene.
New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau
A Phase 1-2 Study of ODM-212 in People With Advanced Solid Tumors
Researchers want to find the best dose of ODM-212 to treat advanced solid tumors. The people in this study have solid tumors that have spread and cannot be cured with standard therapies. Examples include:
New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau
A Phase 2 Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma
Peritoneal mesothelioma is a cancer of the inner lining of the abdomen (belly). The people in this study will be having surgery to take out as much of the cancer as possible. They will also receive heated chemotherapy given directly into the abdomen to kill any remaining cancer cells.
New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau
A Phase 2 Study of Sacituzumab Govitecan in People with Previously Treated Mesothelioma
Sacituzumab govitecan targets and destroys cells that make a protein called TROP-2. Researchers have found this protein to be expressed on mesothelioma cells. By destroying these cells, sacituzumab govitecan may help slow or stop the growth of your cancer. It is given intravenously (by vein).
New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau
A Phase 3 Study of Volrustomig (MEDI5752) in Combination With Carboplatin Plus Pemetrexed in Inoperable Pleural Mesothelioma
If you join this study, you will be randomly assigned to get one of these treatments:
New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau