Clinical Updates & Insights

Our clinical updates provide you with timely information about Memorial Sloan Kettering’s new treatment approaches, key clinical trials, and innovations in detecting and treating many cancers.

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229 Clinical Updates found
T Cell attacking cancer cell
CAR T May Be Beneficial and Safe in Older Patients with Relapsed/Refractory LBCL and Geriatric Vulnerabilities

Older, vulnerable patients with relapsed/refractory large B cell lymphoma should receive the same consideration for CAR T cell therapy as younger patients.
Dr. Joseph Disa
PROs Crucial in Cost Analyses of Reconstruction Options Straight After Mastectomy

When comparing options for immediate breast reconstruction after mastectomy, cost analyses should include patient-reported outcome (PRO) measures, such as BREAST-Q scales and complication rates.
Dr Joachim Yahalom
Very Low-Dose Radiotherapy Effective for Grade 3A Follicular Lymphoma

Very low-dose radiotherapy (VLDRT) is effective for treating grade 3A follicular lymphoma and provides patients with a shorter treatment course and fewer side effects.
Clinical Update
Breast surgeon Dr. Melissa Pilewskie
Breast Density, Not BMI, Linked to Higher Cancer Risk in Lobular Carcinoma in Situ

Increased breast density, but not BMI, is an additional risk factor for breast cancer in women with lobular carcinoma in situ (LCIS).
Clinical Update
lymph nodes
Less Lymphedema with SLN Mapping vs Lymphadenectomy Post Hysterectomy for Endometrial Cancer

Sentinel lymph node (SLN) mapping leads to significantly less lower-extremity lymphedema compared to comprehensive lymphadenectomy (LND) after hysterectomy in patients with endometrial cancer.
Clinical Update
Epidural analgesia for patients with non-small cell lung cancer
Epidural Analgesia Unnecessary in Minimally Invasive Lobectomy

The routine use of epidural analgesia for patients with non-small cell lung cancer who undergo a minimally invasive lobectomy is not warranted.
Clinical Update
Blood pressure reading
Managing Hypertension in Patients Treated with Ibrutinib for Chronic Lymphocytic Leukemia

Blood pressure should be monitored closely and on an ongoing basis for several months after initiating ibrutinib treatment in patients with chronic lymphocytic leukemia (CLL), according to our retrospective study.
Clinical Update
Breast surgery
Axillary MRI Is No Better than a Clinical Exam Alone in Predicting Breast Cancer in Sentinel Nodes after Neoadjuvant Chemotherapy

Magnetic resonance imaging (MRI) of the axilla after neoadjuvant chemotherapy is no more accurate than a clinical exam alone in predicting sentinel lymph node pathology in breast cancer patients with clinical N1 disease.
Clinical Update
HPV and liquid biopsy
MSK Investigators Create a Highly Accurate Liquid Biopsy for Identifying Early-Stage HPV-Associated Oral and Anal Cancers

At MSK we have developed a highly accurate, low-cost assay, for identifying early-stage oral and anal cancers associated with human papillomavirus (HPV) using liquid biopsy.
Clinical Update
Radiation therapy
Reducing Radiation for Select Patients with HPV-Associated Mouth and Throat Cancer

Human papillomavirus (HPV)–associated oropharyngeal cancer is on the rise, but at Memorial Sloan Kettering Cancer Center, we have updated our standard of care to substantially reduce the radiation dose to elective regions.