Clinical Updates & Insights

Our clinical updates provide you with timely information about Memorial Sloan Kettering’s new treatment approaches, key clinical trials, and innovations in detecting and treating many cancers.

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236 Clinical Updates found
William Jarnagin MSK
Clinical Update
What Comes First — Neoadjuvant Chemotherapy or Re-Resection for Patients with Incidental Gallbladder Cancer?

At Memorial Sloan Kettering Cancer Center, more than half of patients with gallbladder cancer are diagnosed incidentally following elective cholecystectomy for assumed benign disease. The traditional treatment approach for these patients is re-resection to achieve a cure.
scientific image
Clinical Update
Rise of the Mutant Clones: A Newly Recognized Risk Factor for CVD

Up to 20 percent of people over the age of 70 have clonal hematopoiesis of indeterminate potential (CHIP), a condition that carries twice the risk of coronary heart disease and ischemic stroke, and worse outcomes after heart failure — independent of traditional cardiovascular risk factors.
Doctor with patient
Clinical Update
Testosterone Recovery Uncertain after Androgen Deprivation Therapy for Prostate Cancer

Androgen deprivation therapy may depress testosterone for prolonged periods in older patients, or those who are on the treatment for more than six months, increasing the risk of associated adverse events, according to the results of our recent retrospective study.
Scientific image
Clinical Update
Immunotherapy and Efficacy of Chemo in Patients with Recurrent Ovarian Cancer

Chemotherapy after immune checkpoint inhibitors (ICIs) may improve survival rates in patients with heavily pretreated, recurrent ovarian cancer.
Patient talking to medical professionals
Clinical Update
Surgery for Advanced Ovarian Cancer Safe in Older Women

Cytoreductive surgery for advanced ovarian cancer is safe in older women, even those who present with frailty.
Ira Dunkel
Clinical Update
New Imaging Method Can Diagnose and Direct Treatment of Rare Pediatric Retinoblastoma

Decreasing values for apparent diffusion coefficient (ADC) mapping derived from MRI may indicate the development of trilateral retinoblastoma in pediatric patients with bilateral retinoblastoma.
Colorectal Liver
Clinical Update
Hepatic Arterial Infusion Converts “Unresectable” Colorectal Liver Mets

The advent of hepatic arterial infusion chemotherapy (HAI) for treating patients with resectable colorectal liver metastases has increased survival outcomes to previously unimaginable levels. However, questions remain about the effectiveness of its use in patients with initially unresectable colorectal liver metastases.
Nai-Kong Cheung, MD, PhD
Clinical Update
New Molecular Signatures of High-Risk Neuroblastoma

High-risk neuroblastoma cells harbor distinguishing molecular signatures, according to recent research.
oligodendroglioma
Clinical Update
Chemotherapy Reduces Seizures in Low-Grade Oligodendroglioma

Temozolomide chemotherapy reduced seizures in 90 percent of patients with World Health Organization (WHO) grade 2 oligodendroglioma and tumor-related epilepsy.
Dr. Anthony F. Yu and patient
Clinical Update
Minimizing Cardiotoxicities of Contemporary Breast Cancer Treatments

In our recently published review paper we provide a comprehensive update on the cardiotoxicities associated with contemporary breast cancer treatment and the latest strategies for their prevention, detection, and management.