2022 Alumni

(From left to right) Top row: Jose Llera Munoz, Sarah Xi, Hans Oh; Bottom row: Isabelle Edmondson, Elizabeth Mari, Casey Chan

Casey Chan
Brown University
Mentor: Yael David
Institution: Memorial Sloan Kettering Cancer Center
Project: Investigating the role of H1.4 phosphorylation on the regulation of DNA replication

Isabelle Edmondson
Middlebury College
Mentor: Dan Bachovchin
Institution: Memorial Sloan Kettering Cancer Center
Project: Thioredoxin stabilizes the NLRP1 inflammasome in an ATP-dependent manner

Jose Llera Munoz
University of Puerto Rico Rio Piedras Campus
Mentor: Samie Jaffrey
Institution: Weill Cornell Medicine
Project: Screening of mutations on the ligand binding pocket of an acyclovir binding RNA aptamer

Elizabeth Mari
Haverford College
Mentor: Jacob Jeri
Institution: Weill Cornell Medicine
Project: Synthesis of Bioorthogonal Photocatalysts for Proximity Labeling Applications

Hans Oh
University of North Carolina Chapel Hill
Mentor: Tarun Kapoor
Institution: Rockefeller University
Project: Synthesis towards chemical probes of PPA, a covalent p97/VCP inhibitor, to investigate AAA proteins

Sarah Xi
Columbia University
Mentor: Ekaterina Vinogradova
Institution: Rockefeller University
Project: Small molecule induction of a unique CD8+CD4+ T cell double positive (DP) phenotype
2021 Alumni

Dominic Covelli
Brown University
Mentor: Daniel Bachovchin
Institution: Memorial Sloan Kettering Cancer Center
Project: Molecular mechanisms underlying inflammasome formation

Julia Flood
Fordham University
Mentor: Yael David
Institution: Memorial Sloan Kettering Cancer Center
Project: Epigenetic regulation of transcription

Amanda Garza
Boston College
Mentor: Yueming Ling
Institution: Memorial Sloan Kettering Cancer Center
Project: Imidazopyrazine based autophagy modulators for Alzheimer’s disease

Maya Huffman
Williams College
Mentor: Derek Tan
Institution: Memorial Sloan Kettering Cancer Center
Project: Direct conversion of carboxylic acids to 3-oxetanol bioisosteres

Abigail Pierre
Seton Hall University
Mentor: Heeseon An
Institution: Memorial Sloan Kettering Cancer Center
Project: PROTAC Degradation of Ribosomal Proteins

Atara Neugroschl
Yeshiva University
Mentor: Daniel Bachovchin
Institution: Memorial Sloan Kettering Cancer Center
Project: A ubiquitin-independent proteasome pathway activates the CARD8 inflammasome
2020 Alumni

Joann Chongsaritsinsuk
University of Richmond, University of St. Andrews
Mentor: Tarun Kapoor
Institution: Rockefeller University
Project: Structural basis for catch bonding between Mdn1 and Rsa4

Samuel Croes
Brown University
Mentor: Lewis Cantley
Institution: Weill Cornell Medicine
Project: Kinome Structure – A Computational Method to Determine Kinase Substrate Specificity

Benjamin Freeman
Princeton University
Mentor: Shuibing Chen
Institution: Weill Cornell Medicine
Project: Human Embryonic Stem Cells (hESC) for replacement therapy and drug discovery

Anna Soltys
Princeton University
Mentor: Derek Tan
Institution: Memorial Sloan Kettering Cancer Center
Project: Using bis-electrophiles to capture Ub tetrahedral intermediates

Charles Warren
University of North Carolina Chapel Hill
Mentor: Daniel Bachovchin
Institution: Memorial Sloan Kettering Cancer Center
Project: Exploring NACHT-LRR Binding Proteins’ Influence on Inflammasome Biology
2019 Alumni

(From left to right) Top row: Christopher Escobar Nieves, Matthew See, Shaochen (Tiger) You; Bottom row: Victoria Rasmussen, Katherine Glaser, Antoinette Antonucci

Antoinette Antonucci
Kean University
Mentor: Tarun Kapoor
Institution: Rockefeller University
Project: Using Chemical Genetics to Design Selective Chemical Probes of VPS4

Katharine Glaser
Barnard College
Mentor: Richard Hite
Institution: Memorial Sloan Kettering Cancer Center
Project: Expression of ClC-7: A Chloride-Proton Transporter

Christopher Nieves Escobar
University of Puerto Rico Humacao
Mentor: Seth Darst
Institution: Rockefeller University
Project: Structural Analysis of a Lasso Peptide Synthetase

Victoria Rasmussen
Providence College
Mentor: Samie Jaffrey
Institution: Weill Cornell Medicine
Project: Discovery of Self-Propargylating Ribozymes in the pursuit of Self-Methylating RNA

Matthew See
University of Michigan
Mentor: Anant Menon
Institution: Weill Cornell Medicine
Project: Synthesis of Mannose-Phosphate Dolichol (MPD) Analogues to Identify MPD Scramblase

Shaochen (Tiger) You
University of Texas Austin
Mentor: Daniel Bachovchin
Institution: Memorial Sloan Kettering Cancer Center
Project: Screening Inhibitors of Human Prolidase Using a Novel Coupled Fluorometric Assay
2018 Alumni

(From left to right) Top row: Angelina Grebe, Nathan Harper, Lauren Vostal; Bottom row: Sophie Kong, Rashmi Rao, Maham Mahmood

Angelina Grebe
Fordham University
Mentor: Howard Hang
Institution: Rockefeller University
Project: Exploration of small GTPase interaction with cytosolic pattern recognition receptors

Nathan Harper
Lafayette College
Mentor: Tarun Kapoor
Institution: Rockefeller University
Project: Biochemical analysis of an Mdn1 intramolecular docking mechanism

Sophie Kong
Bucknell University
Mentor: Daniel Bachovchin
Institution: Memorial Sloan Kettering Cancer Center
Project: The innate immune system

Maham Mahmood
Adelphi University
Mentor: Samie Jaffrey
Institution: Weill Cornell Medicine
Project: Drug targets for post-translational modification

Rashmi Rao
Cornell University
Mentor: John Blenis
Institution: Weill Cornell Medicine
Project: G-quadruplex interactions promote formation of a stable tertiary structure that is critical for fluorescence of aptamer-dye complex

Lauren Vostal
Williams College
Mentor: Minkui Luo
Institution: Memorial Sloan Kettering Cancer Center
Project: HIBCH inhibition in oncogenic KRAS-driven pancreatic ductal adenocarcinoma