2025
Baako AK, Vijayakumar R, Medina-Cano D, Wang Z, Romero-Pichardo J, Fadojutimi K, et al., (2025) Modeling tissue-resident macrophage from mouse pluripotent stem cells. bioRxiv [Preprint]. PMID: 40463197
Castillon VJ, et al., (2025) A health-system-scale, episode-resolved multimodal atlas of cancer cachexia. medRxiv [Preprint]. PMID: 41256140
Jackson BT, Montero AM, Chakraborty S, et al., (2025) Intracellular metabolic gradients dictate dependence on exogenous pyruvate. Nature Metabolism. PMID: 40295877
Kim DV, Chen A, Ng C, Peres-Tintin L, Park SE, Acosta M, Callaghan R, Stanford N, Perez-Rosario M, et al., (2025) E. coli-activated cellular circuit restrains intestinal inflammatory microbiota-specific T cells and protects against colitis. Cell Reports. PMID: 40991928
Narendra VK, Das T, Wierciszewski LJ, Londoner RJ, Morrison JK, Martindale P, Devine T, Chen K, Trombetta M, Kanno Y, Casiano AE, et al., (2025) Independent mechanisms of inflammation and myeloid bias in VEXAS syndrome. Nature.PMID: 41183570
Osman AM, Remsik J, Snyder J, Wijetunga NA, Manoranjan B, Nobre AR, Freret M, Guber D, Chabot K, Piedrafita-Ortiz S, et al., (2025) Autocrine CXCL1-CXCR2 signaling mediates leptomeningeal resistance to radiation therapy. bioRxiv [Preprint]. PMID: 40060386
Pappas K, Ferrari M, Smith P, Nandakumar S, Khan Z, Young SB, et al., (2025) BRCA2 reversion mutation-independent resistance to PARP inhibition through impaired DNA prereplication complex function. Proceedings of the National Academy of Sciences. PMID: 40460119
Paras KI, Brunner JS, Montero AM, Boyer JA, Jackson BT, Chakraborty S, et al., (2025) PAX3-FOXO1 Drives Targetable Cell State-Dependent Metabolic Vulnerabilities in Rhabdomyosarcoma. Cancer Research. PMID: 40911784
Wang Z, Lipshutz A, Martínez de la Torre C, Trzeciak AJ, Liu ZL, Miranda IC, Lazarov T, Codo AC, Romero-Pichardo JE, Nair A, Schild T, Saitz Rojas W, Saavedra PHV, Baako AK, Fadojutimi K, et al., (2025) Early life high fructose impairs microglial phagocytosis and neurodevelopment. Nature. PMID: 40500435
2024
Tang C, Castillon VJ, et al., (2024) Obesity-dependent selection of driver mutations in cancer. Nature Genetics. PMID: 38260500
Tong X, Remsik J, Brook J, Petrova B, Xu L, Li MJ, Snyder J, Chabot K, Estrera R, Osei-Gyening I, Nobre AR, Wang H, Osman AM, Wong AYL, Sidharta M, Piedrafita-Ortiz S, et al., (2024) Retinoid X Receptor Signaling Mediates Cancer Cell Lipid Metabolism in the Leptomeninges. bioRxiv [Preprint] PMID: 39464048
Xiao X, Fay A, Santos Molina P, et al., (2024) Structure of the M. tuberculosis DnaK−GrpE complex reveals how key DnaK roles are controlled. Nature Communications. PMID: 38253530
Waarts MR, Mowla S, Boileau M, Martinez Benitez AR, Sango J, Bagish M, Fernandez-Maestre I, Shan Y, Eisman SE, Park YC, Wereski M, Csete I, O’Connor K, Romero-Vega AC, et al., (2024) CRISPR dependency screens in primary hematopoietic stem cells identify KDM3B as a genotype specific vulnerability in IDH2- and TET2-mutant cells. Cancer Discoveries. PMID:38819218
Zhu Y, Pei X, Novaj A, Setton J, Bronder D, Derakhshan F, Selenica P, McDermott N, Orman M, Plum S, et al., (2024) Large-scale copy number alterations are enriched for synthetic viability in BRCA1/BRCA2 tumors. Genome Medicine. PMID 39198848
2023
Kim D, Herdeis L, Rudolph D, Zhao Y, Böttcher J, Vides A, Ayala-Santos CI, et al., (2023) Pan-KRAS inhibitor disables oncogenic signaling and tumor growth. Nature. PMID: 37258666
Schulze CJ, Seamon KJ, Zhao Y, Ayala-Santos CI, et al., (2023) Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS. Science. PMID: 37590355