Liposarcoma Survival After Initial Surgery


Our liposarcoma nomogram is a tool designed to predict the prognosis of a patient with liposarcoma, the most common soft tissue sarcoma, after the primary tumor has been removed by surgery. This tool predicts the likelihood of surviving five years and 12 years after surgery, based on the characteristics of the patient and the tumor, such as the specific liposarcoma histologic subtype.

Results produced by this tool are based on data from patients treated at MSK, a large research institution with surgeons who perform a high volume of liposarcoma procedures. All results must be understood in the context of each patient’s specific treatment plan. Patients and caregivers using this tool should discuss the result with the patient’s physician.

To gather the information required to use this nomogram, use our worksheet.

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years (10 to 99)
What is histology?
Histology refers to the exact type of cancer based on examination of the tumor tissue under the microscope. Liposarcoma is classified as Well-differentiated; Dedifferentiated; Myxoid; Round Cell; or Pleomorphic.
What are surgical margins?
Margin refers to the edge or border of the tissue removed in cancer surgery. The margin is described as negative or clean when the pathologist finds no cancer cells at the edge of the tissue, suggesting that all of the cancer has been removed. The margin is described as microscopically positive or involved when the pathologist finds traces of cancer cells at the edge of the tissue. The margin is described as grossly positive if the surgeon was unable to remove the entire tumor or all parts of the tumor, implying that a substantial part of the tumor remains in the body.
Note: A tumor is considered to be in the upper extremity if it is in the hand, arm, or at the shoulder joint, and it is considered to be in the lower extremity if it is in the foot, leg, or groin. A tumor is considered to be in the trunk if it is in the chest, back, abdominal wall, or head and neck location. A tumor is retroperitoneal if it is located in the abdominal cavity or retroperitoneal or pelvic space. Retroperitoneal tumors may be removed with or without contiguous organ resection (for example, surgical removal of the kidney, colon, small bowel, pancreas, spleen, bladder, or uterus).
cm (1 to 140)
Note: If you had only one primary tumor, then the tumor burden is simply the largest diameter of that tumor, in centimeters. If you had more than one tumor, add up the largest diameters of each of the tumors.
Note: The depth of the tumor is categorized as either superficial or deep relative to the investing fascia. Depth is considered deep if it involves the superficial fascia or the underlying muscle.
What is fascia?
Fascia refers to a sheet of connective tissue surrounding and binding together body structures, such as muscles, blood vessels, and nerves. The superficial fascia lies under the skin and superficial fat layers and surrounds and binds together the underlying muscles.