Germ Cell and Sex Cord Stromal Tumor Clinical Trials and Research

MSK is a major research institution. At MSK Kids, your child may be able to take part in a clinical trial. Clinical trials are also known as research studies.

What is a clinical trial?

Clinical trials are research studies that test new treatments, procedures, or devices to see how well they work. They are an important part of helping to prevent, treat, and cure cancer. They want to find therapies that work better than current treatments. Nearly every pediatric cancer treatment used today exists because of a clinical trial.

Sometimes a clinical trial gives you access to new therapies that are not yet available at most hospitals.

The children, teens, and young adults we treat have access to the latest clinical trials. Some of these studies are available only at MSK Kids.

Learn about clinical trials at MSK Kids.

Access to national clinical trials for your child

We also take part in many national clinical trials as a founding member of the Children’s Oncology Group. We are the coordinating center and co-founder of the Pediatric Oncology Experimental Therapeutics Investigators’ Consortium. We are also members of other clinical trial networks across the county.

Joining a clinical trial is voluntary. It’s entirely up to you and your family whether you have your child treated through a clinical trial. It’s your choice. Whatever treatment your child gets, our goal is to give them the best care possible.

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4 Clinical Trials found
A Phase 2 Study of a Lower Radiation Therapy Dose to Treat Children and Young Adults With Central Nervous System Germinoma
Researchers are assessing a lower dose of standard radiation therapy after chemotherapy in young people with germinomas. The patients in this study have germinomas of the central nervous system (brain or spinal cord).  It is hoped that this new approach can destroy germinomas with fewer long-term side effects.
New York City
A Phase III Study Evaluating Less Intensive Ways to Treat Germ Cell Tumors
Germ cell tumors (GCTs) include ovarian teratomas and testicular cancers. The standard treatment for "low-risk" GCTs includes complete removal by surgery followed by chemotherapy with cisplatin, bleomycin, and etoposide, unless the patient is a young child, in which case careful observation may be adequate. GCTs are considered "standard risk" if the patient is under age 25 at diagnosis, the tumor was not completely removed during surgery or has spread to other parts of the body, or proteins in the blood called tumor markers are elevated. The standard treatment for standard-risk GCTs includes chemotherapy with cisplatin, bleomycin, and etoposide followed by surgery, followed by more chemotherapy if needed.
New York City
A Phase III Study of Accelerated versus Standard Chemotherapy for Patients with Intermediate- and Poor-Risk Metastatic Germ Cell Tumors
The standard treatment for poor-risk and intermediate-risk germ cell tumors (GCTs), such as testicular cancer, is chemotherapy with the drugs bleomycin, etoposide, and cisplatin (abbreviated BEP) given every three weeks. In this study, researchers want to see if giving BEP chemotherapy every two weeks is more effective for controlling tumor growth than the standard regimen in patients with metastatic intermediate-risk and poor-risk GCTs.
New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau
A Study of ZW251 in People With Solid Tumor Cancer
To learn more about the purpose of this study and to find out who can join, please click here to visit ClinicalTrials.gov for a full clinical trial description.
New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau