Sarcoma Nomograms: Extremity/Truncal Liposarcoma: Disease-Specific Death and Local Recurrence

Prediction Tools: DisclaimerThe prediction tools, also known as prognostic nomograms, located on the MSK Web site are for general health information only. The prediction tools are not to be used as a substitute for medical advice, diagnosis, or treatment of any health condition or problem.Users of the prediction tools should not rely on information provided by the prediction tools for their own health problems. Questions should be addressed to your own physician or other healthcare provider.MSK makes no warranties, nor express or implied representations whatsoever, regarding the accuracy, completeness, timeliness, comparative or controversial nature, or usefulness of any information contained or referenced in the prediction tools. MSK does not assume any risk whatsoever for your use of the prediction tools or the information contained herein. Health related information changes frequently and therefore information contained in the prediction tools may be outdated, incomplete or incorrect.Use of the prediction tools does not create an express or implied physician-patient relationship. MSK does not endorse or claim validity for the prediction tools found on the MSK Web site. The activities and products of MSK and its developers and agents (collectively MSK) are not endorsed by our past, present, or future employers. MSK does not record specific prediction tool user information and does not contact users of the prediction tools.You are hereby advised to consult with a physician or other professional healthcare provider prior to making any decisions, or undertaking any actions or not undertaking any actions related to any healthcare problem or issue you might have at any time, now or in the future. In using the prediction tools, you agree that neither MSK nor any other party is or will be liable or otherwise responsible for any decision made or any action taken or any action not taken due to your use of any information presented in the prediction tools.

Our extremity/truncal liposarcoma nomogram is a tool designed to predict the prognosis of a patient with extremity/truncal liposarcoma, the most common soft tissue sarcoma, after the primary tumor has been removed by surgery. This tool predicts the likelihood of dying from extremity/truncal liposarcoma three years, five years, and ten years after surgical treatment for the disease, based on tumor characteristics, such as the specific liposarcoma histologic subtype. This tool also predicts the likelihood of extremity/truncal liposarcoma returning at the site of initial surgery three years, five years, and ten years after the tumor is removed through surgery.

This nomogram specifically does NOT include retroperitoneal liposarcoma. For patients with retroperitoneal sarcoma, please refer to the sarcoma-specific death and local recurrence nomogram published Annals in Surgery.

Results produced by this tool are based on data from patients treated at MSK, a large research institution with surgeons who perform a high volume of liposarcoma procedures. All results must be understood in the context of each patient’s specific treatment plan. Patients and caregivers using this tool should discuss the result with the patient’s physician.

To gather the information required to use this nomogram, use our worksheet.

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What was the size of your primary tumor? cm (1 to 32)

What was the histologic variant (subtype) of the tumor?

What is histology?: Histology refers to the exact type of cancer based on examination of the tumor tissue under the microscope. Liposarcoma is classified as Well-differentiated; Myxoid; Dedifferentiated; Round Cell; or Pleomorphic.

Were the surgical margins positive?

Yes

What are surgical margins?: Margin refers to the edge or border of the tissue removed in cancer surgery. The margin is described as negative or clean when the pathologist finds no cancer cells at the edge of the tissue, suggesting that all of the cancer has been removed. The margin is described as microscopically positive or involved when the pathologist finds traces of cancer cells at the edge of the tissue. The margin is described as grossly positive if the surgeon was unable to remove the entire tumor or all parts of the tumor, implying that a substantial part of the tumor remains in the body.

Clear

Supporting Publications

Extremity/Truncal Liposarcoma Specific Death After Surgery

Probability of not surviving to ten years after surgery

Bartlett EK, Curtin CE, Seier K, Qin LX, Hameed M, Yoon SS, Crago AM, Brennan MF, Singer S. Histologic Subtype Defines the Risk and Kinetics of Recurrence and Death for Primary Extremity/Truncal Liposarcoma. Ann Surg. 2021 Jun 1;273(6):1189-1196. doi: 10.1097/SLA.0000000000003453. PMID: 31283560; PMCID: PMC7561049.

Extremity/Truncal Liposarcoma Local Recurrence

Probability that extremity/truncal liposarcoma will return within three years, five years, and ten years after surgery

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Supporting Publications

Extremity/Truncal Liposarcoma Specific Death After Surgery

Extremity/Truncal Liposarcoma Local Recurrence