SK-RC-1 is a stage II primary renal carcinoma cell line that grows in nude mice and has a doubling time of 42 hours.
This cell line is from a collection of renal cell carcinoma (RCC) cell lines derived from the primary tumors of patients who underwent surgery. For the complete panel, see (link to SK-RC-(P))
This cell line was established from a 41-year-old male, of unknown ethnicity, with clear cell renal cell carcinoma derived from perinodal adipose tissue.
All cell lines were established in Dr. Lloyd Old’s laboratory, from patients undergoing nephrectomy at Memorial Hospital, MSK, between the years 1972 and 1987. Fresh surgical specimens were obtained from Tumor Procurement Services, Department of Surgical Pathology, Memorial Hospital, MSK.
Lloyd J. Old, MD, former William E. Snee Chair in Cancer Immunology, MSK; former Director, New York Branch, Ludwig Institute for Cancer Research, and members of the Old Laboratory
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- Ueda R et al. (1979) Cell surface antigens of human renal cancer defined by autologous typing. The journal of experimental medicine, 150(3), 564-579. (PubMed ID: 479762)
- Ueda R. et al. (1981) Cell surface antigens of human renal cancer defined by mouse monoclonal antibodies: identification of tissue-specific kidney glycoproteins. Proceedings of the National Academy of Sciences of the United States of America, 78(8), 5122-5126. (PubMed ID: 6946460)
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- RRID: CVCL_4017