Species: Human

Category: Cancer

Tissue of Origin: Brain

Cancer Type: Glioblastoma

Description

TS600 is a human brain cancer cell line.

Source

This cell line was established from a brain metastasis in a person with glioblastoma.

Lead Researcher/Research Laboratory

• Cameron W. Brennan, MD, Laboratory Head, Memorial Hospital Research, Memorial Sloan Kettering Cancer Center
• Ingo Mellinghoff, MD, FACP, Chair, Department of Neurology; Chief Brain Tumor Service, Evnin Family Chair in Neuro-Oncology, MSKCC

Key References

Inda MM, Bonavia R, Mukasa A, Narita Y, Sah DW, Vandenberg S, Brennan C, Johns TG, Bachoo R, Hadwiger P, Tan P, Depinho RA, Cavenee W, Furnari F. Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma. Genes Dev. 2010 Aug 15;24(16):1731-45. doi: 10.1101/gad.1890510. PMID: 20713517; PMCID: PMC2922502.

Licensing Information

This cell line may be licensed nonexclusively for research or commercial purposes.

• Express License: For internal research purposes by a for-profit entity: Fill out MSK’s Core Express License; see here for links to the online fillable Core Express License, as well as a PDF version. For detailed guidance on how to fill out this webform, see here. Please note:  In order to streamline and expedite the licensing of select MSK cell lines, the terms of this non-exclusive license are non-negotiable. This license is only available for select cell lines, including this one. Once this license has been executed by MSK, you will receive a signed copy and payment instructions; all payments up to $10,000 must be made by credit card.
• Commercial License: Contact MSK’s Tangible Research Materials team at [email protected].
• For non-licensing requests from academic-research institutions: Contact MSK’s Antibody & Bioresource Core Facility at [email protected].