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Mission & Goals


Funded by a grant from the National Institutes of Health (NIH), with additional support from the Geoffrey Beene Cancer Research Center, the Center for Precision Disease Modeling aims to translate genome-based knowledge into the development of new therapies for human disease.

A fundamental challenge for medical research is to develop and exploit the most relevant and predictive model systems to understand the physiological impact of the genetic changes associated with these conditions, with the ultimate goal of improving patient care and treatment.


The major goals of the Pilot Center for Precision Disease Modeling are to:

  • coordinate and enhance ongoing genomics, computational, and animal modeling efforts at MSK
  • provide technical infrastructure and support for the Center’s pilot projects
  • make Center capabilities available to MSK investigators and other New York City–based institutions.

Additionally, the Center works with the NIH and other pilot centers to leverage resources to achieve the greatest national impact. The Center provides a blueprint for realizing the potential of human genomics to guide the development of accurate models that can be used to develop novel therapies to ameliorate disease.