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Cell biologist Xuejun Jiang studies programmed cell death, molecular mechanisms, and their roles in tumorigenesis.

… The research of my laboratory focuses on two directions highly relevant to cancer biology, (1) the molecular basis of programmed cell death processes (including apoptosis and ferroptosis), and their roles in human disease; and (2) the molecular basis of autophagy and its role in cancer. We also study

Physician-scientist Sarat Chandarlapaty studies the regulation of growth factor signaling networks in cancer.

… The goal of our research program is to understand the detailed mechanisms by which a cancer cell can develop resistance to therapies targeting its oncogenic driver; and to exploit those findings to elucidate the biology of cancer and identify more effective treatments for cancer patients. The focus of

The Nikolov laboratory focuses on the structural, biophysical, and biochemical characterization of the molecular mechanisms of cell-cell interactions and signal transduction across the plasma membrane.

… Research in our laboratory aims to characterize the molecular mechanisms underlying cell-to-cell interactions and signal transduction across the cell membrane. We are particularly interested in understanding how receptors located on the surface of developing axons and neurons interact with extracellular

Cancer biologist Michael Kharas studies RNA regulators of self-renewal in both normal and leukemic hematopoiesis.

… The Kharas lab is working to identify critical pathways in both normal and leukemic hematopoietic cells. Michael G. Kharas, PhD Professor PhD, University of California Irvine Achievements Leukemia and Lymphoma Society Career Development Award (2017) Alex Lemonade Stand Foundation ‘A’ Award (2016) American

Physician-scientist Nai-Kong Cheung focuses on engineering antibodies and immune cells to treat both solid tumors and liquid tumors in children.

… My lab focuses on engineering antibodies and immune cells to treat both solid tumors and liquid tumors in children. Nai-Kong V. Cheung, MD, PhD Enid A. Haupt Chair in Pediatric Oncology, Pediatrics Professor MD, PhD (Immunology), Harvard Medical School Email [email protected] Laboratory phone 646-888

Biomedical engineer Daniel Heller is Head of the Cancer Nanotechnology Laboratory, which invents disruptive technologies to revolutionize the diagnosis and treatment of cancer and allied diseases.

… Cancer Nanomedicine Laboratory We are a biomedical engineering laboratory that develops nanotechnologies to advance breakthroughs in the research, diagnosis, and treatment of cancer and allied diseases. We develop drug delivery technologies to target therapies to disease sites, advanced diagnostics to

Immunologist Ming Li studies mechanisms of immune regulation, and their relevance to diseases including cancer.

… The pervasive influence of the immune system on human health and disease underscores the importance of a mechanistic understanding of immune regulation under pathophysiological conditions such as cancer. Cancer immunology research in my laboratory aims to decipher the cellular and molecular basis of

Physician-scientist Ingo Mellinghoff studies signal transduction alterations in primary brain tumors.

… Our laboratory focuses on the study of molecular pathways that regulate brain tumor growth. Our long-term goal is to develop therapeutic paradigms that target specific properties of primary brain tumors, including genetic alterations in cancer signaling pathways, unique aspects of brain tumor metabolism

We take real-world data, clean it and use it to discover new predictive biomarkers to guide cancer management (often with AI), and then implement these findings in clinical practice.

… AI and real-world data are alluring tools, which may transform the practice of oncology. But the integration and application of these tools to cancer research and clinical care has to improve at every step before they can meaningfully improve the lives of patients.  To develop useful biomarkers, we need

Immunologist Morgan Huse studies the structure and function of immune cell-cell interactions.

… In the Huse lab, we combine imaging technology with synthetic chemistry and materials science to understand how immune cells communicate. Morgan Huse, PhD Deputy Director for Core Technologies; Member, Immunology Program Professor PhD, The Rockefeller University Achievements Searle Scholar Award (2008