Memorial Hospital Research Laboratories
The Nai-Kong Cheung Lab
My lab focuses on engineering antibodies and immune cells to treat both solid tumors and liquid tumors in children.
Santich BH, Park JA, Tran H, Guo HF, Huse M, Cheung NV. Interdomain spacing and spatial configuration drive the potency of IgG-[L]-scFv T cell bispecific antibodies. Sci Transl Med. 2020;12(534). [reprint] [text]
Souweidane MM, Kramer K, Pandit-Taskar N, Zhou Z, Haque S, Zanzonico P, Carrasquillo JA, Lyashchenko SK, Thakur SB, Donzelli M, Turner RS, Lewis JS, Cheung NV, Larson SM, Dunkel IJ. Convection-enhanced delivery for diffuse intrinsic pontine glioma: a single-centre, dose-escalation, phase 1 trial. Lancet Oncol. 2018 Jun 15. pii: S1470-2045(18)30322-X. doi: 10.1016/S1470-2045(18)30322-X.
Kushner BH, Cheung IY, Modak S, Basu EM, Roberts SS, Cheung NK. Humanized 3F8 anti-GD2 monoclonal antibody dosing with granulocyte-macrophage colony-stimulating factor in patients with resistant neuroblastoma – A Phase 1 Clinical Trial. JAMA Oncol. 2018 September 20. doi:10.1001/jamaoncol.2018.4005
Hoseini SS, Guo HF, Wu ZH, Hatano MN, Cheung NKV. A potent tetravalent T-cell-engaging bispecific antibody against CD33 in acute myeloid leukemia. Blood Advances 2(11):1250-1258, 2018
Nai-Kong V. Cheung, MD, PhD
Enid A. Haupt Chair in Pediatric Oncology, Pediatrics
- Physician-scientist Nai-Kong Cheung focuses on engineering antibodies and immune cells to treat both solid tumors and liquid tumors in children.
- MD, PhD (Immunology), Harvard Medical School
- [email protected]
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Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
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Nai-Kong V. Cheung discloses the following relationships and financial interests:
Intellectual Property Rights; Ownership / Equity Interests; Provision of Services
Intellectual Property Rights
Eureka Therapeutics Inc
Ownership / Equity Interests
Japanese Society of Hematology
Provision of Services (uncompensated)
National Institutes of Health (NIH)
Provision of Services
Y-mAbs Therapeutics, Inc.
Intellectual Property Rights; Ownership / Equity Interests
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