Memorial Hospital Research Laboratories

The Nai-Kong Cheung Lab

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Research

The Nai-Kong Cheung Lab
Nai-Kong V. Cheung, MD, PhD
Enid A. Haupt Chair in Pediatric Oncology, Pediatrics

My lab focuses on engineering antibodies and immune cells to treat both solid tumors and liquid tumors in children.

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Nai-Kong Cheung Lab Group

Featured News

Dr. Nai-Kong V. Cheung, Head, Neuroblastoma Program; Enid A. Haupt Chair in Pediatric Oncology
At Work: Physician-Scientist Nai-Kong Cheung

Meet pediatric oncologist Nai-Kong Cheung, whose research into solid tumors is creating new hope for children with cancer.

Publications

Santich BH, Park JA, Tran H, Guo HF, Huse M, Cheung NV. Interdomain spacing and spatial configuration drive the potency of IgG-[L]-scFv T cell bispecific antibodies. Sci Transl Med. 2020;12(534). [reprint] [text]

Souweidane MM, Kramer K, Pandit-Taskar N, Zhou Z, Haque S, Zanzonico P, Carrasquillo JA, Lyashchenko SK, Thakur SB, Donzelli M, Turner RS, Lewis JS, Cheung NV, Larson SM, Dunkel IJ.  Convection-enhanced delivery for diffuse intrinsic pontine glioma: a single-centre, dose-escalation, phase 1 trial.  Lancet Oncol. 2018 Jun 15. pii: S1470-2045(18)30322-X. doi: 10.1016/S1470-2045(18)30322-X.

Kushner BH, Cheung IY, Modak S, Basu EM, Roberts SS, Cheung NK.  Humanized 3F8 anti-GD2 monoclonal antibody dosing with granulocyte-macrophage colony-stimulating factor in patients with resistant neuroblastoma – A Phase 1 Clinical Trial.  JAMA Oncol. 2018 September 20. doi:10.1001/jamaoncol.2018.4005

Hoseini SS, Guo HF, Wu ZH, Hatano MN, Cheung NKV.  A potent tetravalent T-cell-engaging bispecific antibody against CD33 in acute myeloid leukemia.  Blood Advances 2(11):1250-1258, 2018

Wu ZH, Guo HF, Xu H, Cheung NKV.  Development of a tetravalent anti-GPA33/anti-CD3 bispecific antibody for colorectal cancers. Mol Cancer Ther. 2018 Aug 6. pii: molcanther.0026.2018. doi: 10.1158/1535-7163.MCT-18-0026.

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People

The Nai-Kong Cheung Lab

Nai-Kong V. Cheung, MD, PhD

Enid A. Haupt Chair in Pediatric Oncology, Pediatrics

  • Physician-scientist Nai-Kong Cheung focuses on engineering antibodies and immune cells to treat both solid tumors and liquid tumors in children.
  • MD, PhD (Immunology), Harvard Medical School
[email protected]
Email Address
646-888-2313
Office Phone
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Physician profile

Members

Irene Cheung, ScD
Irene Cheung

Laboratory Member and Attending Clinical Immunologist

Madelyn Espinosa-Cotton
Madelyn Espinosa-Cotton

Research Fellow

Yi Feng
Yi Feng

Senior Research Assistant

Hong-fen Guo
Hong-fen Guo

Research Assistant/Specialist

Alan Long, PhD
Alan Long

Research Scholar

Aiza Malik
Aiza Malik

Research Technician

Jeong Park
Jeong A Park

Research Fellow

Mauricio Rendon-Bernot, MD
Mauricio Rendon-Bernot

Clinical Fellow

Hoa Tran
Hoa Tran

Senior Research Assistant

Hong Xu
Hong Xu

Senior Research Scientist

Yiwei Liu

Senior Research Scientist

Lab Alumni
Sayed Shahabuddin (Shahab) Hoseini
Sayed Shahabuddin (Shahab) Hoseini

Research Associate

Tsung-Yi (Steven) Lin, PhD
Tsung-Yi (Steven) Lin

Research Fellow

Brian Santich
Brian H. Santich

Research Fellow

Linlin Wang , PhD
Linlin Wang

Research Associate

Mao (Sally) Wang, PhD
Mao (Sally) Wang

Research Fellow

Lab Affiliations

Open Positions

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Nai-Kong V. Cheung discloses the following relationships and financial interests:

  • Abpro Inc
    Intellectual Property Rights; Ownership / Equity Interests; Provision of Services
  • Biotec Pharmacon
    Intellectual Property Rights
  • Eureka Therapeutics Inc
    Ownership / Equity Interests
  • Japanese Society of Hematology
    Provision of Services (uncompensated)
  • National Institutes of Health (NIH)
    Provision of Services
  • Y-mAbs Therapeutics, Inc.
    Intellectual Property Rights; Ownership / Equity Interests

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.

This page and data include information for a specific MSK annual disclosure period (January 1, 2021 through disclosure submission in spring 2022). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].


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