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The Kushal Dey lab focuses on developing machine learning models and computational pipelines that integrate genomic and epigenomic data.

… The Kushal Dey Lab builds statistical and machine learning models that integrate genetic and genomic data to prioritize variants, genes, and cell types, and to decode the causal functional architecture underlying heritable complex diseases — including immune-related diseases, like Alzheimer’s and inflammatory

The Pertsinidis laboratory uses single-molecule approaches to understand gene transcription and the function of complex macromolecular machines inside live cells.

… Our mission is the development of a “new” generation of optical imaging technologies to enable advances in two hitherto difficult-to-investigate areas: the real-time analysis of macromolecular interactions and motions at the nanometer scale in vivo and the three-dimensional architecture of complex molecular

The Tulpule lab studies how cells compartmentalize critical cellular processes with a focus on biomolecular condensates in cancer.

… The Tulpule Lab is interested in a long-standing question in cell biology: how do cells organize and compartmentalize critical cellular processes within the crowded and heterogeneous intracellular space? We focus on an emerging set of self-assembling, protein-based structures known as biomolecular condensates

Cancer biologist and pediatric oncologist Alex Kentsis leads research in the functional proteomics and molecular pharmacology of refractory childhood cancers.

… We study the biology of cancers that affect children and young adults ranging from embryonal tumors in infants, leukemias and brain tumors in children, and sarcomas in young adults. Scientists in our group use inter-disciplinary experimental tools as they work to understand the fundamental causes of

Optical engineer Milind Rajadhyaksha studies confocal microscopy for the imaging of cancer, technology development, and translational and clinical studies in skin and head and neck cancers.

… I am a mechanical and optical engineer and principal investigator in the Optical Imaging Laboratory in the Dermatology Service. My research focuses on creating novel confocal microscopes and endoscopes for imaging skin and head and neck cancers, and translating this technology to clinical applications

Molecular biologist Thomas Kelly studies regulatory mechanisms that control DNA replication during the cell cycle of eukaryotic cells.

… My long-term interest is to understand how the cellular genome is duplicated during the cell cycle. In the course of growth and division, eukaryotic cells duplicate their genomes with remarkable fidelity. The precision of this process depends in large measure upon stringent regulatory mechanisms that

We leverage large-scale unbiased profiling including genomics, transcriptomics, proteomics to identify candidate oncogenes and proteins that are pathogenetically relevant in lymphoma.

… Kojo S. Elenitoba-Johnson is the Chair of the Department of Pathology and Laboratory Medicine and a physician-scientist. Dr. Elenitoba-Johnson’s research focuses on the role of genomic and proteomic alterations in the pathogenesis of lymphomas. Dr. Megan S. Lim is the Director of the Lymphoma Translational

The Antonsecu lab focuses on translocation-associated sarcoma pathogenesis and generating in vitro models.

… An on-going focus of our work is the genomic investigation of pediatric and young adult unclassified mesenchymal tumors, with a special emphasis on detecting novel gene fusions drivers. By applying highly efficient RNAseq and FusionSeq pipelines for novel translocation discovery in tumors that lack known

Physician-scientist Babak Mehrara studies the regulation of lymphatic regeneration after surgery and development of lymphedema.

… Our research group focuses on the lymphatic system in three different pathological settings: lymphedema, obesity, and cancer. Chronic lymphedema is a morbid disease condition without any cure. Our first goal is to uncover the pathology behind development and progression of cancer-related secondary lymphedema

Dr. Solomon is an interventional radiologist whose team investigates novel minimally invasive, image-guided therapies and their biologic and immunologic interactions.

… Our lab develops new minimally invasive image-guided cancer treatments: Methods for improving the anti-tumor immune response after embolization or ablation. Genetic, imaging, and other tests to predict response after embolization or ablation. New devices for endoluminal ablation (ureter, bile ducts,