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Research Lab
The Functional MRI Laboratory provides pre-operative planning for patients with brain tumors and studies the clinical applications of advanced neuroimaging techniques for brain tumor imaging.
… Our lab utilizes functional, diffusion, and perfusion MRI to provide pre-operative planning for patients with brain tumors. The goal of our work is to identify key areas of the brain, such as areas for language, motor, sensory, and auditory function, prior to treatment so that neurosurgical interventions
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Research Lab
The Shah lab focuses on the major topics of cancer evolution, single cell genomics and transcriptomics, mutational processes and prediction of drug response.
… The Shah lab focuses on the major topics of cancer evolution, single cell genomics and transcriptomics, mutational processes and prediction of drug response. We are interested in the major questions which underpin the cellular dynamics of cancer. Why do some cancer patients respond to treatment, while
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Research Lab
Radiochemist Jason Lewis develops molecular imaging agents for the imaging and therapy of cancer.
… The Lewis lab research interests are focused on the development of radiopharmaceuticals for targeted diagnosis and treatment of cancer. By combining small- and biomolecule-based targeting agents with positron-emitting or therapeutic radioisotopes, we can interrogate molecular profiles of cancer using
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Research Lab
The Choi Lab develops new synthetic biology tools to study cell-fate decisions in development.
… The Choi Lab develops new synthetic biology tools to study cell-fate decisions in development. During development, cells differentiate into various cell types with distinct functions. To understand how different cell types are made, we need a tool to observe cells’ previous and current states, as well
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Research Lab
Optical engineer Milind Rajadhyaksha studies confocal microscopy for the imaging of cancer, technology development, and translational and clinical studies in skin and head and neck cancers.
… I am a mechanical and optical engineer and principal investigator in the Optical Imaging Laboratory in the Dermatology Service. My research focuses on creating novel confocal microscopes and endoscopes for imaging skin and head and neck cancers, and translating this technology to clinical applications
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Research Lab
Molecular biologist Thomas Kelly studies regulatory mechanisms that control DNA replication during the cell cycle of eukaryotic cells.
… My long-term interest is to understand how the cellular genome is duplicated during the cell cycle. In the course of growth and division, eukaryotic cells duplicate their genomes with remarkable fidelity. The precision of this process depends in large measure upon stringent regulatory mechanisms that
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Research Lab
Computational biologist Ruslan Soldatov develops computational methods to study cell fate decisions and somatic evolution in normal tissues and cancer.
… The Soldatov Lab aims to characterize the mechanisms of cell fate decisions that coordinate tissue function and quantify how distortions of these mechanisms shape the course of cancer evolution. We are broadly interested in using a large-scale data science approach to study questions related to the organization
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Research Lab
Molecular geneticist Britta Weigelt studies the genomics of gynecologic cancers and the use of circulating cell-free DNA for disease monitoring and the identification of therapy resistance mechanisms.
… Gynecology DMT Research Laboratory Our laboratory focuses on the use of high-throughput genomics and functional genomics to identify drivers of rare gynecologic cancer types, and to define the clinical and biological significance of intra-tumor phenotypic and genetic heterogeneity in these tumors. Dr
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Research Lab
Arvin Dar’s lab develops chemical tools and probes to explore disease mechanisms and the structural biology of cancer targets.
… The Dar laboratory explores cancer mechanisms and new approaches in chemical biology. Our research integrates genetics, biochemistry, structure, and small molecule discovery. Our primary goal is to develop tools that enable us to modulate cell signaling networks, allowing for in-depth mechanistic exploration
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Research Lab
Molecular and cell biologist Christine Mayr studies how 3′UTRs regulate protein functions and how mRNAs contribute to cytoplasmic organization.
… My laboratory studies the regulatory and structural roles of mRNAs in the cytoplasm. My laboratory studies the regulatory and structural roles of mRNAs in the cytoplasm. Specifically, we investigate how 3′UTRs regulate protein functions in a manner that is independent of protein abundance. We found that