Full Title
A First In Human Phase I, Open Label, Safety And Tolerability Study of Escalating Multiple Doses of Intratumoral MQ710, A Multi-Transgene Expressing Modified Vaccinia Virus Ankara-Based Virotherapy, Alone and in Combination with The Systemic Checkpoint Inhibitor Pembrolizumab in Solid TumorsPurpose
In this study, researchers are finding the highest dose of MQ710 to use safely in people with certain types of advanced cancer. The people in this study have solid tumors that came back or grew even after treatment. In a later part of the study, the researchers will assess MQ710 plus another drug called pembrolizumab.
MQ710 is a type of immunotherapy. It is made to kill tumor cells directly as well as boost your own immune system to fight cancer. It is injected directly into tumors.
Contact
For more information and to see if you can join this study, please contact Dr. Lara Dunn’s office at 646-608-3787.
Protocol
22-278
Phase
Phase I (phase 1)
Disease Status
Relapsed or Refractory
Investigator
Co-Investigators
Diseases
Locations
ClinicalTrials.gov ID
NCT05859074
ClinicalTrials.gov