A Phase 2 Study of Limited Radiation Therapy After Surgery in People With Tongue Cancer


Full Title

Phase 2 Single Arm Trial of Adjuvant Nodal Irradiation Alone in Post Operative Oral Tongue Squamous Cell Carcinoma


Doctors routinely use intensity-modulated radiation therapy (IMRT) after surgery to treat squamous cell carcinoma (cancer) of the tongue. IMRT delivers radiation directly to cancer cells from different angles by changing the radiation beam into multiple smaller beams. By targeting the tumor more precisely, IMRT reduces radiation damage to healthy tissue.

IMRT usually targets the part of the tongue where cancer surgery was done. It is also aimed at lymph nodes under the tongue and along both sides of the neck. Researchers want to learn if limiting IMRT to exclude the tongue surgical site can lower the risk of side effects. That is the purpose of this study.

Who Can Join

To join this study, there are a few conditions. You must:

  • Have squamous cell carcinoma of the tongue that has or will be removed with surgery.
  • Be age 18 or older.


For more information or to see if you can join this study, please call Dr. Sean McBride’s office at 646-608-2450.




Phase II (phase 2)

Disease Status

Newly Diagnosed & Relapsed/Refractory


ClinicalTrials.gov ID