
Nancy Y. Lee, MD, FASTRO
Radiation Oncologist
Titles
Vice Chair, Experimental Therapeutics, Department of Radiation Oncology; Service Chief, Head & Neck Radiation Oncology; Service Chief, Proton Therapy
Clinical Expertise
Head and Neck Cancers; Skin Cancers; Thyroid Cancer; Mouth Cancer
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New Patient Appointments
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Dr. Lee accepts the following list of insurance providers. Select your insurance provider to see more details.
Payor Type: Commercial
In Network Coverage Type(s): HMO, EPO PPO, POS, Transplant
Payor Type: Medicare/Medicare Advantage
In Network Coverage Type(s): PPO
Payor Type: Commercial
In Network Coverage Type(s): HMO, PPO
Payor Type: Commercial
In Network Coverage Type(s): PPO, POS, EPO, HMO
Payor Type: Commercial
In Network Coverage Type(s): HMO, EPO PPO, POS
Payor Type: Medicaid/Managed Medicaid
In Network Coverage Type(s): HMO
Payor Type: Commercial
In Network Coverage Type(s): Supplemental
Payor Type: Commercial
In Network Coverage Type(s): PPO, POS, HMO
Payor Type: Commercial
In Network Coverage Type(s): POS, EPO, HMO
Payor Type: Commercial
In Network Coverage Type(s): PPO, POS, EPO, HMO
Payor Type: Medicaid/Managed Medicaid
In Network Coverage Type(s): HMO
Payor Type: Medicare/Medicare Advantage
In Network Coverage Type(s): PPO, HMO
Payor Type: Medicare/Medicare Advantage
In Network Coverage Type(s): PPO, HMO, DSN
Payor Type: Medicaid/Managed Medicaid
In Network Coverage Type(s): HMO
Payor Type: Commercial
In Network Coverage Type(s): PPO
Payor Type: Commercial
In Network Coverage Type(s): HMO, EPO
Payor Type: Medicaid/Managed Medicaid
In Network Coverage Type(s): HMO
Payor Type: Medicare/Medicare Advantage
In Network Coverage Type(s): HMO
Payor Type: Medicare/Medicare Advantage
In Network Coverage Type(s): PPO
Payor Type: Commercial
In Network Coverage Type(s): EPO, HMO, PPO, POS
Payor Type: Medicaid/Managed Medicaid
In Network Coverage Type(s): HMO
Payor Type: Medicare/Medicare Advantage
In Network Coverage Type(s): HMO, PPO
Payor Type: Commercial
In Network Coverage Type(s): PPO EPO
Payor Type: Commercial
In Network Coverage Type(s): HMO
Payor Type: Commercial
In Network Coverage Type(s): PPO
Payor Type: Commercial
In Network Coverage Type(s): EPO
Payor Type: Commercial
In Network Coverage Type(s): EPO
Payor Type: Medicare/Medicare Advantage
In Network Coverage Type(s): PPO, HMO
Payor Type: Medicaid/Managed Medicaid
In Network Coverage Type(s): State Government
Payor Type: Commercial
In Network Coverage Type(s): PPO, POS, EPO
Payor Type: Medicaid/Managed Medicaid
In Network Coverage Type(s): State Government
Payor Type: Medicaid/Managed Medicaid
In Network Coverage Type(s): State Government
Payor Type: Medicare/Medicare Advantage
In Network Coverage Type(s): Federal Government
Payor Type: Commercial
In Network Coverage Type(s): Supplemental
Payor Type: Commercial
In Network Coverage Type(s): PPO/OAP
Payor Type: Other
In Network Coverage Type(s): PPO, POS, EPO, HMO
Payor Type: Medicare/Medicare Advantage
In Network Coverage Type(s): TBD
Payor Type: Commercial
In Network Coverage Type(s): HMO/EPO
Payor Type: Commercial
In Network Coverage Type(s): PPO, EPO
Payor Type: Commercial
In Network Coverage Type(s): State Government
Payor Type: Commercial
In Network Coverage Type(s): PPO, POS, HMO
Payor Type: Commercial
In Network Coverage Type(s): PPO, HMO
Payor Type: Commercial
In Network Coverage Type(s): PPO, POS
Payor Type: Commercial
In Network Coverage Type(s): PPO, POS, HMO
Contact and Location
- 212-639-3341 Office Phone
- Speaks English and Mandarin

Memorial Sloan Kettering has locations throughout New York City, Long Island, New Jersey, and Westchester. These locations offer many services, including screening, chemotherapy, and medical testing.
See all locationsAbout Me
Education
MD, University of Medicine and Dentistry of New Jersey
Residencies
Radiation Oncology - Columbia Presbyterian Medical Center
Board Certifications
Radiation Oncology
I am a radiation oncologist with more than 17 years of experience. I specialize in using advanced forms of radiation to treat head and neck cancer, including thyroid cancer. These include proton therapy, intensity modulated radiation therapy, image-guided radiation therapy, and stereotactic body radiation therapy. My goal in using these technologies is to improve my patients’ outcomes while decreasing potential treatment side effects and preserving their quality of life. No matter which treatment option we use, I care for all of my patients as if they were part of my family. This means creating a plan tailored to their unique disease, and doing everything I can to help them get well.
Read more
There are many effective treatment options for people diagnosed with tumors in the head and neck. We can get rid of many of these tumors without the need for an invasive surgery. Instead, we can use radiation therapy alone or in combination with immunotherapy, targeted therapy, or chemotherapy. This is especially true for tumors in the tonsils, base of the tongue, and soft palate.
People who come to me for their care never see only me. I believe it’s important to consult with my colleagues in medical oncology and surgery. All of my patients benefit from the combined expertise of several doctors who are committed to curing their cancer and helping them get back to their lives.
My research is focused on ways to make radiation therapy for head and neck cancers safer and more effective. I am the principal investigator for many national and international clinical trials. For example, for people with very advanced head and neck cancer, I am researching the effectiveness of immunotherapy combined with chemoradiation. I am also studying the use of plasma Epstein-Barr virus DNA to individualize treatment for people with nasopharyngeal cancer.
In recent years, we have seen a rise in cases of head and neck cancer caused by the human papilloma virus (HPV). Though these cancers may respond to conventional therapies, we need to find innovative new ways to treat them. I am one of the leading experts in this area. I am currently leading a trial to evaluate the use of smaller radiation doses for select people with HPV-related head and neck cancers. These smaller doses mean we can help people avoid possible side effects from extensive radiation.
I am also very active in many cooperative groups such as NRG Oncology and National Cancer Institute committees. I have authored numerous articles focusing on head and neck cancers with the goal of defining appropriate treatment for people with these diseases. I am one of the major thought leaders in the world for the treatment of head and neck cancer.
People who are diagnosed with cancer may feel hopeless. When I meet with patients, I always try to restore their hope by clearly explaining treatment options, answering questions, and discussing any concerns. I also remind them that even though we will work to make their tumor go away, I won’t be going anywhere; I will be with them every step of the way and will continue to see them for the rest of their lives.
All of my patients benefit from the combined expertise of several doctors who are committed to curing their cancer and helping them get back to their lives.
-Dr. Lee
Awards and Honors
- Castle Connolly: America's Top Doctors (2023)
- Castle Connolly: New York Magazine Top Doctors (2013-2020)
Colleagues
Doctors at Memorial Sloan Kettering work as teams, with specialists from all different areas. This allows us to consider all your needs together, and to give you the best possible care.
See all Early Drug Development Service doctors
See all Radiation Oncology doctors
See all External Beam Radiotherapy Service, Manhattan doctors
See all Brachytherapy Service doctors
Clinical Trials
- Clinical Trials Investigated by Dr. Lee
- A Phase II Study of Proton versus Photon Beam Radiotherapy to Treat Head and Neck Cancer
- A Study Assessing a Major Dose Reduction in Radiation Therapy for HPV-Positive Oropharyngeal Cancer
- A Study of Customized Treatment for Nasopharyngeal Cancer Based on Epstein-Barr Virus DNA
- A Study of RP-3500 in Combination with Standard Radiation Therapy to Treat Symptoms in People with Metastatic Solid Tumors
Read more
- A Study of Significantly Reduced Radiation Therapy and Reduced Chemotherapy in People with HPV-Positive Throat Cancer
- Clinical Trials Co-Investigated by Dr. Lee
- A Phase I/II Study of [225Ac]-FPI-1434 in People with Advanced or Metastatic Solid Tumors
- A Phase I/II Study of [225Ac]-FPI-1966, [111In]-FPI-1967, and Vofatamab in People with Advanced Solid Tumors
- A Phase III Study of Pembrolizumab Immunotherapy Before Surgery and in Combination with Standard Therapy After Surgery for Stage III-IVA Head and Neck Cancer
- A Phase III Study of Penpulimab or Placebo Plus Chemotherapy in People with Recurrent or Metastatic Nasopharyngeal Carcinoma
- A Study Assessing Cell-Free Tumor DNA Testing to Decide When to Start Routine Treatment in People with Human Papilloma Virus (HPV)-Associated Oropharynx Cancer

Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.
You may be able to participate in a clinical trial even if you are new to MSK. Search our online directory to find trial information and see more about who can participate.
Search clinical trialsResearch and Publications
Visit PubMed for a full listing of Dr. Lee’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.
See all on PubMedPatient Reviews
At MSK, we’re committed to delivering the best care to every patient. We use feedback from our patients to continue to improve our care. We also post patient reviews online to help you make healthcare choices. Learn more about our patient experience reviews.
Disclosures
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Nancy Y. Lee discloses the following relationships and financial interests:
-
Elsie Biotechnologies, Inc.
Provision of Services -
Merck & Co Inc.
Provision of Services -
Merck Serono
Provision of Services
-
Mirati Therapeutics
Provision of Services -
Roche
Provision of Services
If you’re a patient at MSK and would like more information about your doctor’s external relationships, please talk with your doctor.
The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.
This page and data include information for a specific MSK annual disclosure period (January 1, 2021 through disclosure submission in spring 2022). This data reflects interests that may or may not still exist. This data is updated annually.
Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].