At any time Memorial Sloan Kettering Cancer Center is conducting hundreds of clinical trials to improve care for many types of cancer. Use the tool below to browse our clinical trials that are currently enrolling new patients. Each listing explains the purpose of the trial, the trial’s eligibility criteria, and how to get more information.
The list below includes clinical trials for adult cancers. Please visit our pediatric cancer care section to find a pediatric clinical trial.
Memorial Sloan Kettering offers language assistance services for those who prefer to receive health information in another language. Learn more about our language assistance program here.
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Peritoneal mesothelioma is a cancer of the inner lining of the abdomen (belly). The people in this study will be having surgery to take out as much of the cancer as possible. They will also receive heated chemotherapy given directly into the abdomen to kill any remaining cancer cells.
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After endometrial cancer surgery, there is a risk that the cancer will come back. Combining a shorter course of radiation treatment with chemotherapy may decrease the chance of endometrial cancer recurring.
- A Study to See if Heart Cells Can Be Generated from Blood or Skin Cells of Breast Cancer Patients
Full Title Generation of Induced Pluripotent Stem Cell Derived Cardiomyocytes from Patients Exposed to Trastuzumab Therapy for Breast Cancer
Purpose
Patients receiving certain drugs for breast cancer, such as doxorubicin or trastuzumab, may experience impaired heart function. Researchers at Memorial Sloan Kettering Cancer Center are conducting a study to see if it is possible to grow heart muscle cells (“cardiomyocytes”) from blood or skin cells from breast cancer patients. The skin cells will be grown in a special mixture in the laboratory designed to transform them from skin cells into heart muscle cells.
Researchers will then study the structure and function of these cells to determine why some patients who receive breast cancer drugs experience reduced heart function. The findings of this study could potentially be used to improve the heart function of patients receiving these medications for breast cancer.
Who Can Join
Participants in this study will include women with breast cancer who have been treated with doxorubicin followed by trastuzumab, or trastuzumab alone.
For more information about this study, please contact Dr. Richard Steingart at 212-639-8488.
Protocol
16-025Phase
Pilot (small research study)Investigator
Co-Investigators
Richard SteingartDiseases
Locations
ClinicalTrials.gov ID
NCT02772367ClinicalTrials.gov
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Azacitidine turns on genes that help control cell growth. It is given intravenously (by vein) or by injection.
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Researchers want to see if ASTX727 is practical and safe for people with high-risk clonal cytopenia of undetermined significance (CCUS). With CCUS, there is a mutation (change) in one or more of the genes that help blood cells develop. People with CCUS have low levels of certain kinds of blood cells. CCUS can lead to precancerous conditions such as myelodysplastic syndrome or blood cancers such as acute myeloid leukemia.
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Normally when people have B-cell lymphoma that is not in complete remission, they do not immediately have another treatment. They have observation. That means their doctor closely monitors their disease with imaging tests to see if their disease is improving or worsening. If their disease gets worse, they may receive more treatment.
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Researchers want to see if bulumtatug fuvedotin works well against breast cancer. The people in this study have triple-negative breast cancer (TNBC) that came back or spread after treatment. 
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The purpose of this study is to assess the feasibility of a new approach to treat people with T4 breast cancer who have already received chemotherapy. T4 breast cancer occurs when the cancer has grown beyond normal breast tissue and into the chest wall or skin or has become swollen and causes pain. Doctors normally treat T4 breast cancer with chemotherapy followed by mastectomy and removal of underarm (axillary) lymph nodes. After mastectomy, patients normally receive radiation therapy and then have breast reconstruction surgery many months to years after completing radiotherapy.
- A Study Comparing Music Therapy and Cognitive Behavioral Therapy for Anxiety in Cancer Survivors
Full Title Music Therapy vs. Cognitive-Behavioral Therapy for Cancer-related Anxiety (MELODY)
Purpose
Many cancer survivors suffer from anxiety. Anxiety may involve feelings of restlessness, muscle tension, and worry. Anxiety has also been linked to poor sleep, depressed mood, and tiredness. Researchers are doing this study to see how music therapy and cognitive behavioral therapy may be able to reduce anxiety and these other symptoms. Both music therapy and cognitive behavioral therapy are routinely used to treat anxiety.
Cognitive behavioral therapy is based on the idea that thoughts, feelings, and actions are all connected. It is a type of talk therapy (therapy focusing on conversations between a patient and healthcare provider) that helps a person change their thought patterns and behavior. Music therapy uses music to encourage healing and promote a sense of well-being. It can include listening to music to help relax and making music by singing or writing a song.
In this study, the music therapy and cognitive behavioral therapy sessions will be virtual, meaning that they will take place online rather than in person. Participants will be randomly assigned to receive one type of therapy or the other, but not both.
Who Can Join
To be eligible for this study, patients must meet several requirements, including:
- Participants must have completed cancer treatment at least one month before entering the study. They must also be experiencing anxiety or worry lasting at least one month.
- Patients must have no evidence of cancer.
- Patients must speak English or Spanish.
- This study is for people age 18 and older.
For more information about this study, please contact the Clinical Research Coordinator at 646-449-1028 or email [email protected].
Protocol
21-516Phase
Phase IV (phase 4)Investigator
Co-Investigators
Locations
ClinicalTrials.gov ID
NCT05215353ClinicalTrials.gov
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BV-AVD is a combination of drugs used to treat advanced (stage 3 or 4) Hodgkin lymphoma. Researchers in this study want to see how well it works to treat early-stage bulky Hodgkin lymphoma. The people in this study have stage 1 or 2 bulky Hodgkin lymphoma that has not yet been treated.