Andrew D. Seidman, MD
Breast Medical Oncologist
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About Me
- Attending Physician
I am an experienced medical oncologist who has spent three decades caring for people with breast cancer. I specialize in treating all subtypes and stages of breast cancer, from the earliest to the most advanced stages of the disease. I have special expertise in the understanding and treatment of breast cancer that has metastasized (spread) to the brain, a condition that has historically been managed primarily by radiation oncologists and neurosurgeons.
I typically see more than 1,000 patients each year, both remotely and in person. The pandemic has taught us that we can treat patients’ disease and improve well-being both ways, but I much prefer to see patients in person.
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Patients and their loved ones are naturally concerned about how breast cancer will affect their survival and quality of life. The large amount of information available on the internet often leads people to feel overwhelmed and confused. My goal is to provide them with expert, evidence-based guidance in terms of diagnosis, prognosis, and treatment, along with humane and compassionate care. I trust that this, along with the tremendously skilled team that works with me, reassures patients and leaves them feeling hopeful, optimistic, realistic, and secure in the knowledge that they are in capable and caring hands here at Memorial Sloan Kettering Cancer Center (MSK).
For me, oncology, more than any other specialty, demands a deep understanding of physiology, genetics/genomics, and humanity — and represents a great unmet need. Meaningful and rewarding patient experiences during my residency in internal medicine, an early exposure to outpatient medical oncology practice, and strong role models were important factors in my decision to become an oncologist.
Outcomes for people with breast cancer have steadily improved over the past 30 years, thanks to a tremendous increase in the understanding of underlying biology that has informed advances in surgical, medical, and radiation treatment. As the last chemotherapy drug for breast cancer was introduced well over a decade ago, there has been a shift away from conventional toxic chemotherapy to targeted therapies, which generally have fewer side effects. It has been exciting for me to be a part of this movement by designing and leading phase 1, 2, and 3 clinical trials.
My research has focused on studying new chemotherapeutic agents and targeted drugs for the treatment of metastatic breast cancer. Over the past decade, I have worked to identify better medical therapies to improve outcomes for people with breast cancer metastasis to the brain. I continue to lead and engage in interdisciplinary research in this area with my colleagues at MSK and beyond. These ongoing efforts will likely lead to changes in the way patients are treated in coming years.
Overall, I subscribe to a “work hard, play hard” philosophy! In my spare time, I enjoy biking, hiking, skiing, gardening, baking, and reading. I recently organized a book club that meets every three months, which has been especially enjoyable. I cherish the time I get to spend with my family and look forward to being able to travel more easily to see the world as the pandemic subsides.
A breast medical oncologist is a cancer doctor who specializes in breast cancer.
My Specialties
- Breast Cancer
Education
- MD, Hahnemann University School of Medicine
Residencies
- Internal Medicine - Pennsylvania Hospital
Awards and Honors
- Castle Connolly: America’s Top Doctor (2024)
- Top Doctors New York Metro Area, Castle Connolly (2023)
- Castle Connolly: America's Top Doctors (2023)
Fellowships
- Medical Oncology/Hematology - Memorial Sloan Kettering Cancer Center
Board Certifications
- Internal Medicine
- Medical Oncology
Insurance Information
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If you have questions about insurance, call us at 646-497-9176.
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Contact and Location
Dr. Seidman sees patients at one location.
Looking to see a doctor at a different location? See all MSK locations.
Colleagues
Doctors at Memorial Sloan Kettering work as teams, with specialists from all different areas. I work closely with nurse practitioner Rachel Motzer. We combine our expertise to provide comprehensive care to our patients at every step of their cancer journey.
Clinical Trials
- Clinical Trials Investigated by Dr. Seidman
- A Study of Tucatinib Given Before Surgery to People with HER2-Positive Cancers That Have Spread to the Brain
- Clinical Trials Co-Investigated by Dr. Seidman
- A Phase I/II Study of Olaparib and Stereotactic Radiosurgery Followed by Durvalumab and Chemotherapy in People with Breast Cancer That Has Spread to the Brain
Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.
You may be able to participate in a clinical trial even if you are new to MSK. Search our online directory to find trial information and see more about who can participate.
Search clinical trialsResearch and Publications
Morikawa A, Grkovski M, Patil S, Jhaveri KL, Tang KL, Humm JL, Holodny A, Beal K, Schöder H, Seidman AD. A phase I trial of sorafenib with whole brain radiotherapy (WBRT) in breast cancer patients with brain metastases and a correlative study of FLT-PET brain imaging. Breast Cancer Res Treat 2021.
Seidman AD, Maues J, Tomlin T, Bhatnagar V, Beaver JA. The evolution of clinical trials in metastatic breast cancer: Design features and endpoints that matter. Am Soc Clin Oncol Educ Book 40:1-11, 2020.
Tripathy D, Cortes J, Seidman AD, et al. ATTAIN: Etirinotecan Pegol Versus Treatment of Physician’s Choice in Patients with Breast Cancer and Brain Metastases. Future Oncology 15(19):2211-25, 2019.
Seidman AD, Bordeleau L, Fehrenbacher L et al. National Cancer Institute Breast Cancer Steering Committee Working Group Report on Meaningful and Appropriate End Points for Clinical Trials in Metastatic Breast Cancer. J Clin Oncol 36(32):3259-68, 2018. Special Article
Morikawa A, Patil S, Diab A, Yang J, Hudis CA, McArthur HL, Beal K, Seidman AD. Characteristics and prognostic factors for patients with HER2-overexpressing breast cancer with brain metastasis in the era of HER-2 targeted therapy: An argument for earlier detection. Clin Breast Cancer 18(5):353-361, 2018.
Morikawa A, Peereboom DM, Thorsheim HR, Samala R, Balyan R, Murphy CG, Lockman PR, Simmons A, Weil RJ, Tabar V, Steeg PS, Smith QR, Seidman AD. Capecitabine and lapatinib uptake in surgically resected brain metastases from metastatic breast cancer patients: a prospective study. Neuro-Oncol 17(2):289-95, 2015.
Brogi E, Murphy CG, Johnson ML, Conlin AK, Hsu M, Patil S, Akram M, Nehhozina T, Jhaveri KL, Hudis CA, Seidman AD. Breast carcinoma with brain metastases: clinical analysis and immunoprofile on tissue microarrays. Ann Oncol 22(12):2597-603, 2011.
Seidman AD, Berry D, Cirrincione C, Harris L, Muss H, Marcom PK, Gipson G, Burstein H, Lake D, Shapiro CL, Ungaro P, Norton L, Winer E, Hudis C. Randomized phase III trial of weekly compared with every-3-weeks paclitaxel for metastatic breast cancer with trastuzumab for all HER-2 overexpressors and random assignment to trastuzumab or not in HER-2 nonoverexpressors: final results of Cancer and Leukemia Group B protocol 9840. J Clin Oncol 26(10):1642-1649, 2008.
Visit PubMed for a full listing of Dr. Seidman’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.
See all on PubMedPatient Reviews
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Disclosures
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Andrew D. Seidman discloses the following relationships and financial interests:
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3D Communications
Professional Services and Activities -
AstraZeneca
Professional Services and Activities -
Cancer Expert Now, Inc.
Professional Services and Activities -
Eli Lilly and Company
Professional Services and Activities -
Exact Sciences Corporation
Professional Services and Activities -
G1 Therapeutics
Professional Services and Activities -
Genentech
Professional Services and Activities -
Gilead Sciences, Inc.
Professional Services and Activities -
Hackensack University Medical Center
Professional Services and Activities
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Mashup Media, LLC
Professional Services and Activities -
Merck & Co Inc.
Professional Services and Activities -
myMedEd, Inc.
Professional Services and Activities -
Novartis
Professional Services and Activities -
PSI Pharma Support America
Professional Services and Activities -
SMB Consulting
Professional Services and Activities -
Stemline Therapeutics, Inc.
Professional Services and Activities -
Virginia Oncology Associates
Professional Services and Activities
If you’re a patient at MSK and would like more information about your doctor’s external relationships, please talk with your doctor.
The information published here is a complement to other publicly reported data and is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.
This page and data include information for a specific MSK annual disclosure period (January 1, 2023 through disclosure submission in spring 2024). This data reflects interests that may or may not still exist. This data is updated annually.
Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].