MSK Dialog Window

Meet Cardinale Smith: Thoracic Medical Oncologist at MSK

Dr. Cardinale Smith treats lung cancer at MSK, combining years of experience with research to deliver tailored, compassionate treatment and improved access to care.
Video Details
Dr. Cardinale Smith

Cardinale Smith, MD, PhD

Areas of Expertise

Conditions I Treat

  • Small cell lung cancer (SCLC)
  • Non-small cell lung cancer (NSCLC)
  • Thymoma

My Specialties

  • Palliative care
Request an Appointment
Our Care Advisors can answer many of your questions. They will connect you with the best healthcare provider for your needs.

Get to Know Me

I am a thoracic medical oncologist who has special training in treating all types of lung cancer. This includes non-small cell lung cancer, small cell lung cancer, and thymoma. I am also an expert in palliative medicine. Palliative care for cancer helps manage symptoms and the side effects of cancer and its treatment to improve a person’s quality of life.

I see patients at Memorial Hospital, the main hospital at Memorial Sloan Kettering Cancer Center (MSK), and at MSK Westchester.

Besides my clinical role, I serve as Chief Medical Officer (CMO) at MSK. In this role, I manage clinical quality, patient safety, regulatory compliance, and clinical operations across the institution. As CMO, my goal is to foster the best treatment results for patients, and support and empower our teams. I also aim to continue advancing excellence and safety across the organization in everything we do.

I make sure our medical staff follows high standards of care, safety, and compliance so that every person gets the best quality of care possible. I also make sure that our team of doctors, nurses, advanced practice providers (APPs), and non-clinical staff, is fully supported and can do their best work every single day.

Born to an immigrant family, I grew up hearing how my mother’s dream to become a physician was sidelined by the barriers faced by women of color. Although she redirected her passion into a career as a school social worker, she made it her life’s mission to remove any obstacle in my path to becoming a doctor. Her sacrifices and support have given me a sense of deep dedication to social justice and health equity. These are principles that have helped shape my worldview.

When I meet with a patient, I approach their care as a partnership. I listen to their concerns, goals, and values. With their feedback, I create a treatment plan that is not only based on data but is also focused on their unique needs. My goal is that people understand the risks and benefits of each option and feel comfortable making decisions based on their values and preferences.

My research focuses on improving the quality of care for people with cancer, developing new models for delivering equitable cancer care, and improving communication between patients and physicians. I am currently involved in a research study funded by the National Institutes of Health. This study looks at how a cancer doctor’s attitudes or beliefs can affect communication and clinical results.

I am also conducting research funded by the American Cancer Society’s Cancer Health Research Centers. The goal of this research is to assess community-based navigation and the factors that can be a barrier to accessing cancer care.

When I am not working, I enjoy spending time with my family and reading fantasy fiction.

What I Do at MSK

I'm a thoracic medical oncologist, which is a cancer doctor who specializes in thoracic (thor-A-sik) cancers. These are cancers that have to do with the chest, including lung, tracheal (windpipe), and thymic (thymus) cancers.

  • Chief Medical Officer
Areas of Expertise

Conditions I Treat

  • Small cell lung cancer (SCLC)
  • Non-small cell lung cancer (NSCLC)
  • Thymoma

My Specialties

  • Palliative care
Education & Honors

Education

  • MD, Drexel University College of Medicine
  • Master of Science (MS) in Clinical Research, Mount Sinai School of Medicine Graduate School of Biomedical Sciences
  • PhD, Clinical Research, Icahn School of Medicine at Mount Sinai (ISMMS) Graduate School of Biomedical Sciences

Residencies

  • Internal Medicine, Mount Sinai School of Medicine

Fellowships

  • Hematology/Medical Oncology and Palliative Medicine, Mount Sinai School of Medicine

Board Certifications

  • Hospice and Palliative Medicine
  • Medical Oncology

Awards and Honors

  • The Mount Sinai Graduate School Alumni Award, Icahn School of Medicine at Mount Sinai (2023)
  • Executive Leadership in Academic Medicine (ELH) Participant, Drexel University College of Medicine (2022)
  • Next Gen Innovator Award, HemOnc Today (2019)
  • Sojourns Scholar Leadership Program, Cambia Health Foundation (2018)
  • Leadership Development Program, American Society of Clinical Oncology (ASCO) (2017)

Insurance Information

Understanding your insurance options is an important part of managing your cancer care. We have relationships with many common healthcare providers and plans.

Don't see your carrier or plan? We can help you understand your coverage.

If you don't have health insurance or are worried that your care may not be fully covered, our financial assistance programs may be able to help.

If you have questions about insurance, call us at 646-497-9176.

Make an Appointment

Current Patients
Request an appointment by calling your Care Team or messaging them in MSK MyChart.

Contact and Location

Office Phone
Location
West Harrison, NY
New York, NY
500 Westchester Avenue West Harrison NY 10604
1275 York Avenue New York NY 10065

Looking to see a doctor at a different location? See all MSK locations.

Colleagues

Doctors at Memorial Sloan Kettering work as teams, with specialists from all different areas. This allows us to consider all your needs together, and to give you the best possible care.

See all Thoracic Oncology Service doctors

Clinical Trials

Smiling doctors in the lab
Find a Clinical Trial for You

Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.

You may be able to participate in a clinical trial even if you are new to MSK. Search our online directory to find trial information and see more about who can participate.

Search clinical trials

Research and Publications

Publications on PubMed

Visit PubMed for a full listing of Dr. Smith’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.

See all on PubMed

Disclosures

Members of the MSK Community often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community. These activities outside of MSK further our mission, provide productive collaborations, and promote the practical application of scientific discoveries.

MSK requires doctors, faculty members, and leaders to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public. Not all disclosed interests and relationships present conflicts of interest. MSK reviews all disclosed interests and relationships to assess whether a conflict of interest exists and whether formal COI management is needed.

Cardinale Smith discloses the following relationships and financial interests:

  • American Cancer Society
    Professional Services and Activities (Uncompensated)
  • American Society of Clinical Oncology (ASCO)
    Professional Services and Activities (Uncompensated)
  • Daymark Health, Inc.
    Equity; Professional Services and Activities
  • Rubin Paterniti Gonzalez Rizzo Kaufman, LLP
    Professional Services and Activities

If you’re a patient at MSK and would like more information about your doctor’s external relationships, please talk with your doctor.

The information published here is a complement to other publicly reported data and is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.


This page and data include information for a specific MSK annual disclosure period (January 1, 2024 through disclosure submission in spring 2025). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].


View all disclosures