Diana E. Lake, MD

Medical Oncologist

Conditions Treated

Diana E. Lake, MD
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About Me

I am a medical oncologist with a practice that is devoted solely to the care of people with breast cancer. My research interests involve all areas of breast cancer but focus mainly on the development of new therapies, prevention of cancer recurrence following surgery, and treatment of recurrent disease. Working in conjunction with my colleagues on the Breast Medicine Service, and in breast, surgical, and radiation, and as the liaison in breast medicine to Cancer and Leukemia Group B (a national clinical trial cooperative research group sponsored by the National Cancer Institute), I am involved in clinical trials to develop better hormonal therapies and improved approaches to treatment before surgery. In addition, I am a member of the National Institutes of Health (NIH) Scientific Review Committee, and I previously served on the NIH Cooperative Group Review and its Cancer Education committees.

I work closely with nurse practitioner Danielle Alleva. We combine our expertise to provide comprehensive care to our patients at every step of their cancer journey. 

  • Clinical Expertise: Breast Cancer
  • Languages Spoken: English
  • Education: MD, Chicago Medical School
  • Residencies: Pathology - New York Hospital/Cornell University Medical College; Internal Medicine - North Shore University Hospital
  • Fellowships: Hematology/Oncology - Memorial Sloan Kettering Cancer Center
  • Board Certifications: Internal Medicine; Medical Oncology; Hematology

See My Colleagues


Dawson N, Lake D, et al. A randomized study comparing standard vs. moderately high dose megace acetate in prostate cancer. CALGB Study 9181. Cancer 2000; 88: 825-34.

Easaw S, Lake DE, Beer M, Seiter K, Feldman E, Ahmed T. Graft-Versus-Host Disease: Possible Higher Risk for African-American Patients. Cancer 1996; 78: 1492-1497.

Lake DE, Kunzweiler J, Beer M, Buell DN, Islam MZ. Fluconazole versus Amphotericin B in the Treatment of Esophageal Candidiasis in Cancer Patients. Chemotherapy 1996; 42: 308-314.

Marchalonis JJ, Schluter SF, Wang E, Dehhanpisheh K, Lake D, Yocum DE, Edmnundson AB, Windfield JB. Synthetic autoantigens of immunoglobulins and t-cell receptors: Their recognition in aging, infection, and autoimmunity. Pro Soc Exper Bio Med 1994; 207: 129-47.

Goldenberg D, Sharkey R, Hall T, Mortly S, Siegel, Izon D, Swayne C, Lake D, Hansen H, Pinsky C. Radio-immunotherapy of B-Cell lymphomas with 131-I-labeled L12 (EPB-2) monoclonal antibody. Antibody Immunoconjugate Radio-pharmaceuticals 1991; 4: 763-769.

Alzarka A, Haft J, Bassil H, Goldstein J, Arkel Y, Lake-Lewin D. Correlation of cross-linked fibrin degradation products (D-Dimers) with coronary angiographic lesion morphology. Int J Cardiol 1991; 30:77.

Kris MG, Pablo D, Gralla RJ, Burke T, Prestifilippo J, Lake-Lewin D. Pulmonary toxicity following vinblastine administration in patients receiving mitocycin plus vinca alkaloid combination therapy. Cancer Treat Reports 68, 1019-1031.

Yen A, Lake-Lewin D. Uncoupling lymphocyte proliferation from differentiation:dissimilar dose response relations pokeweek mitogen induced proliferation and differentiation of normal human lymphocytes. Cellular Immunol 1981; 61: 332, 1981.

Lake-Lewin D, Meyers J, Lee B, Young C. Phase III study of lyrazofurin (PZF) in the treatment of multiple myeloma refractory to standard cytotoxic therapy. Cancer Treat Reports. 1979; 63:1403.

Lake-Lewin D, Schulman P. An unusual case of extramedullary myeloma with metastatic features. JAMA 1979; 242:65.


Visit PubMed for a full listing of Diana E. Lake’s journal articles

Pubmed is an online index of biomedical articles maintained by the U.S. National Library of Medicine and the National Institutes of Health.

Clinical Trials

Research is integral to our mission at Memorial Sloan Kettering, and clinical trials help us discover better forms of patient care and treatment. For you, this could mean access to a new therapy or therapy combination. Click to see a list of the trials I’m currently leading.


Most major health insurers offer plans that include MSK as one of their in-network providers. If MSK is in-network, it means all our doctors are too. Medicare and New York State Medicaid also provide benefits for care at MSK.

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