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Fei Ye, PhD
Director, Assay Development
Molecular Diagnostics in Clinical Oncology, Bone Marrow Transplantation Monitoring, and HLA-Associated Diseases; Molecular Genetics; Molecular Virology
MS, Norman Bethune University of Medical Sciences, Changchun, China; PhD, Norman Bethune University of Medical Sciences, Changchun, China
Molecular Immunology - Tongji Medical University, Wuhan, China
New York State Department of Health Certificate of Qualification in Transplant Monitoring, Oncology, Virology, and Molecular Genetics
I am a clinical laboratory scientist and have almost 20 years of clinical expertise in molecular biology, assay development, and validation of laboratory developed tests. Over the years, I have developed, validated, and implemented clinical molecular assays in transplant monitoring, oncology, infectious diseases, and genetics. In addition, I have a demonstrated record of successful and productive research and translational projects in areas of high relevance for cancer biology. As Director of Assay Development, I lead the technical direction of validating and implementing HLA-related molecular tests in the Immunogenomics of Transplantation and Cellular Therapy Laboratory, as well as expanding the department’s clinical and translational research innovation. This includes work such as molecular and proteomic biomarker discovery, circulating micro RNA-based assays, and next-generation sequencing.
My research has been mainly focused on therapeutic and diagnostic biomarker discovery. Through my work I have seen that that dysregulation of a network of protein-protein interactions (rather than one or a few proteins) in a cell leads to transformation, invasion, and metastasis of the cancer cells, and each subnetwork presents a different phenotype of cancer. I have a strong interest in collaborating with MSK clinical investigators to study the signaling pathways and networks that are targeted by cancer development and progression of anticancer drugs. We are working to further identify biomarkers and druggable targets for cancer diagnosis and treatment.
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Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Fei Ye discloses the following relationships and financial interests:
No disclosures meeting criteria for time period
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