Jeffrey P. Greenfield, MD, PhD

Jeffrey P. Greenfield, MD, PhD

Pediatric Neurosurgeon

Clinical Expertise

Pediatric Neurosurgery; Pediatric Brain Tumors; Neuroendoscopy; Minimally Invasive Neurosurgery; Spinal Cord Tumors

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Accepted Insurance Providers

Dr. Greenfield accepts the following list of insurance providers. Select your insurance provider to see more details.

Contact and Location

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Memorial Sloan Kettering has locations throughout New York City, Long Island, New Jersey, and Westchester. These locations offers many services, including screening, chemotherapy, and medical testing.

About Me


MD, PhD, Weill Cornell Medical College


NewYork-Presbyterian Hospital/Weill Cornell Medical Center


Children's Hospital of Philadelphia

Board Certifications

Neurological Surgery

I am a fellowship-trained pediatric neurosurgeon who specializes in the surgical treatment of cancerous and noncancerous disorders affecting the brain and spine. With regard to cancer, I have clinical expertise in the use of minimally invasive “endoscopic” approaches to surgery for tumors at the base of the skull, such as those in or near the pituitary gland including pituitary tumors, craniopharyngiomas and tumors of the clivus. As part of a skull base team, I am able to remove these tumors through the nose. By avoiding incisions on the head, this approach does not leave external scars and is far less painful and traumatic for children.

I also specialize in patients with a type of brain tumor called low-grade astrocytoma. To the naked eye, these tumors look very much like normal brain tissue. I am able to use MRI in the operating room to distinguish between normal and tumor tissue, allowing for precise and maximal removal of tumor tissue. We also use advanced techniques to map the parts of the brain responsible for language and motor function before and during surgery so we can avoid these areas during an operation and safely remove these invasive tumors.

In my research, I am seeking to understand the events that transform benign tumors such as low-grade astrocytomas into malignant tumors. We have demonstrated that certain cells from the bone marrow travel to the brain and promote the development of the blood vessels that tumors need to grow and spread. My colleagues and I are seeking to develop a way to monitor certain cells in the blood to see if we can predict which tumors are most likely to become malignant, enabling us to provide treatment early to keep a tumor in a chronic, benign state. We are also examining the role these cells have in the metastatic spread or dissemination of other malignant tumors, including medulloblastoma.

We are performing molecular characterization of a type of tumor called brainstem glioma, which currently has no cure, with the hope of designing therapies targeted directly to the cause of this devastating childhood brain tumor. I started and am leading the Pediatric Brain Tumor Collaborative between Memorial Sloan Kettering and Weill Cornell Medical Center, where I also have an appointment. The mission of this effort is to drive the development and conduct of new clinical trials, using a multidisciplinary approach.

I truly draw inspiration from my young patients every day. I keep the goal of a happy productive childhood and continued physical, emotional, and intellectual development in mind with every treatment decision we make with our patients and their families.


Doctors at Memorial Sloan Kettering work as teams, with specialists from all different areas. This allows us to consider all your needs together, and to give you the best possible care.

Clinical Trials

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Find a Clinical Trial for You

Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.

You may be able to participate in a clinical trial even if you are new to MSK. Search our online directory to find trial information and see more about who can participate.

Research and Publications

Publications on PubMed

Visit PubMed for a full listing of Dr. Greenfield’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.