Jessica Chapman-Lim

Jessica R. Chapman, PhD

Areas of Expertise

Conditions I Treat

  • Light chain (AL) amyloidosis

My Specialties

  • Mass spectrometry-based proteomics
  • Biomarker testing
  • Hematopathology

Get to Know Me

I am a bioanalytical chemist who specializes in mass spectrometric analysis of peptides and proteins. My primary clinical responsibility is the interpretation of mass spectrometry-based proteomics clinical assay results. As a laboratory director, I am responsible for the management and oversight of the Clinical Proteomics Laboratory. This includes the development and validation of novel assays for the identification and quantitation of proteins and peptides that will facilitate precision medicine. I work closely with pathologists and oncologists to identify unmet clinical diagnostic and prognostic needs.

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My current research interests include the development of methods for the detection and quantitation of clinically relevant biomarkers. One specific area of focus are methods for tracking disease in patients with myeloma and Amyloid light-chain (AL) amyloidosis.

 

What I Do at MSK

I'm a pathologist-scientist at MSK. This is a doctor with special training in researching why a disease happens and how it changes over time.

  • Director, Clinical Proteomics
Areas of Expertise

Conditions I Treat

  • Light chain (AL) amyloidosis

My Specialties

  • Mass spectrometry-based proteomics
  • Biomarker testing
  • Hematopathology
Education & Honors

Education

  • PhD, University of Virginia

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Contact and Location

Dr. Chapman sees patients at one location.

Office Phone
Location
New York, NY
1275 York Avenue New York NY 10065

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Colleagues

Doctors at Memorial Sloan Kettering work as teams, with specialists from all different areas. This allows us to consider all your needs together, and to give you the best possible care.

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Clinical Trials

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Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.

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Research and Publications

View a list of Dr. Chapman’s publications.

Chapman JR, Liu A, Yi SS, Hernandez E, Ritorto MS, Jungbluth AA, Pulitzer M, Dogan A. Proteomic analysis shows that the main constituent of subepidermal localised cutaneous amyloidosis is not galectin-7. Amyloid. 2020 Sep 1;1-7. PMID: 32867548.

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Martins CO, Huet S, Yi SS, Ritorto MS, Landgren O, Dogan A, Chapman JR. Mass Spectrometry-Based Method Targeting Ig Variable Regions for Assessment of Minimal Residual Disease in Multiple Myeloma. J Mol Diagn. 2020, 22(7):901-911. PMID: 32302778.

Martins CO, Lezcano C, Yi SS, Landau HJ, Chapman JR, and Dogan, A. Novel iatrogenic amyloidosis caused by peptide drug liraglutide: a clinical mimic of AL amyloidosis. Haematologica. 2018, 103(12), e610 – e612. PMID: 30262557

Chapman, J.R., Katsara, O., Ruoff, R., Morgenstern, D., Nayak, S., Basilico, C., Ueberheide, B., and Kolupaeva, V. Phosphoproteomics of FGF1 signaling in chondrocytes: Identifying the signature of inhibitory response. Mol. Cell Proteomics. 2017, 16(6), 1126 – 1137. PMID: 28298517

Chapman, J.R., Balasubramanian, D., Tam, K., Askenazi, M., Copin, R., Shopsin, B., Torres, V.J., and Ueberheide, B. Using quantitative mass spectrometry to better understand the influence of genetics and nutritional perturbations on the virulence potential of Staphylococcus aureus. Mol. Cell Proteomics. 2017, 16(4), S15-S28. PMID: 28196877

Publications on PubMed

Visit PubMed for a full listing of Dr. Chapman’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Jessica R. Chapman discloses the following relationships and financial interests:

No disclosures meeting criteria for time period


If you’re a patient at MSK and would like more information about your doctor’s external relationships, please talk with your doctor.

The information published here is a complement to other publicly reported data and is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.


This page and data include information for a specific MSK annual disclosure period (January 1, 2023 through disclosure submission in spring 2024). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].


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