Memorial Sloan Kettering medical oncologist Joseph Chan

Joseph Minhow Chan, MD, PhD

Medical Oncologist

Titles

Instructor

Clinical Expertise

Lung Cancer; Non-Small Cell Lung Cancer; Small Cell Lung Cancer; Small Cell Lung Cancer Transformation

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800-525-2225
Monday through Friday, 8:00 a.m. to 6:00 p.m., (Eastern time)
Accepted Insurance Providers

Dr. Chan accepts the following list of insurance providers. Select your insurance provider to see more details.

Aetna

Payor Type: Commercial
In Network Coverage Type(s): HMO, EPO PPO, POS, Transplant

Aetna Medicare Advantage (City of NY retirees only, starting 9/1/23)

Payor Type: Medicare/Medicare Advantage
In Network Coverage Type(s): PPO

Blue Cross Blue Shield Federal Employee Program

Payor Type: Commercial
In Network Coverage Type(s): HMO, PPO

Blue Cross Blue Shield New York

Payor Type: Commercial
In Network Coverage Type(s): PPO, POS, EPO, HMO

Blue Cross Blue Shield states outside of NY/NJ

Payor Type: Commercial
In Network Coverage Type(s): HMO, EPO PPO, POS

Blue Cross Health Plus

Payor Type: Medicaid/Managed Medicaid
In Network Coverage Type(s): HMO

Carrum Health

Payor Type: Commercial
In Network Coverage Type(s): Supplemental

Cigna

Payor Type: Commercial
In Network Coverage Type(s): PPO, POS, HMO

Connecticare

Payor Type: Commercial
In Network Coverage Type(s): POS, EPO, HMO

Emblem

Payor Type: Commercial
In Network Coverage Type(s): PPO, POS, EPO, HMO

Emblem Essential

Payor Type: Medicaid/Managed Medicaid
In Network Coverage Type(s): HMO

Emblem Medicare Advantage

Payor Type: Medicare/Medicare Advantage
In Network Coverage Type(s): PPO, HMO

Empire Blue Cross Medicare Advantage

Payor Type: Medicare/Medicare Advantage
In Network Coverage Type(s): PPO, HMO, DSN

Empire Essential

Payor Type: Medicaid/Managed Medicaid
In Network Coverage Type(s): HMO

Empire Plan / NYSHIP (Blue Cross/UnitedHealthcare split plan)

Payor Type: Commercial
In Network Coverage Type(s): PPO

Fidelis

Payor Type: Commercial
In Network Coverage Type(s): HMO, EPO

Fidelis Managed Medicaid & HARP

Payor Type: Medicaid/Managed Medicaid
In Network Coverage Type(s): HMO

Fidelis Medicare Advantage

Payor Type: Medicare/Medicare Advantage
In Network Coverage Type(s): HMO

First Health

Payor Type: Medicare/Medicare Advantage
In Network Coverage Type(s): PPO

Healthfirst

Payor Type: Commercial
In Network Coverage Type(s): EPO, HMO, PPO, POS

Healthfirst Managed Medicaid

Payor Type: Medicaid/Managed Medicaid
In Network Coverage Type(s): HMO

Healthfirst Medicare Advantage

Payor Type: Medicare/Medicare Advantage
In Network Coverage Type(s): HMO, PPO

Healthsmart

Payor Type: Commercial
In Network Coverage Type(s): PPO EPO

Horizon Blue Cross Blue Shield New Jersey (HMO)

Payor Type: Commercial
In Network Coverage Type(s): HMO

Horizon Blue Cross Blue Shield New Jersey (PPO)

Payor Type: Commercial
In Network Coverage Type(s): PPO

Horizon Blue Cross Blue Shield New Jersey Omnia Tier I (EPO)

Payor Type: Commercial
In Network Coverage Type(s): EPO

Horizon Blue Cross Blue Shield New Jersey Omnia Tier II (EPO)

Payor Type: Commercial
In Network Coverage Type(s): EPO

Horizon Medicare Advantage

Payor Type: Medicare/Medicare Advantage
In Network Coverage Type(s): PPO, HMO

Husky CT Medicaid

Payor Type: Medicaid/Managed Medicaid
In Network Coverage Type(s): State Government

Magnacare

Payor Type: Commercial
In Network Coverage Type(s): PPO, POS, EPO

Straight NJ Medicaid

Payor Type: Medicaid/Managed Medicaid
In Network Coverage Type(s): State Government

Straight NY Medicaid

Payor Type: Medicaid/Managed Medicaid
In Network Coverage Type(s): State Government

Medicare Part A&B (traditional Medicare)

Payor Type: Medicare/Medicare Advantage
In Network Coverage Type(s): Federal Government

Multiplan/Beech Street/PHCS

Payor Type: Commercial
In Network Coverage Type(s): Supplemental

MVP

Payor Type: Commercial
In Network Coverage Type(s): PPO/OAP

Non-Participating Plans with Out of Network Benefits

Payor Type: Other
In Network Coverage Type(s): PPO, POS, EPO, HMO

NYC Medicare Advantage Plus for City Employees

Payor Type: Medicare/Medicare Advantage
In Network Coverage Type(s): TBD

Oscar

Payor Type: Commercial
In Network Coverage Type(s): HMO/EPO

Oxford

Payor Type: Commercial
In Network Coverage Type(s): PPO, EPO

World Trade Center Health Program (WTC)

Payor Type: Commercial
In Network Coverage Type(s): State Government

Qualcare

Payor Type: Commercial
In Network Coverage Type(s): PPO, POS, HMO

Tricare

Payor Type: Commercial
In Network Coverage Type(s): PPO, HMO

UMR

Payor Type: Commercial
In Network Coverage Type(s): PPO, POS

United Healthcare

Payor Type: Commercial
In Network Coverage Type(s): PPO, POS, HMO

Contact and Location

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Find a Convenient Location

Memorial Sloan Kettering has locations throughout New York City, Long Island, New Jersey, and Westchester. These locations offer many services, including screening, chemotherapy, and medical testing.

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About Me

Education

MD, Columbia University; PhD, Columbia University

Residencies

Internal Medicine - Weill Cornell at New York Presbyterian

Fellowships

Medical Oncology - Memorial Sloan Kettering

Board Certifications

Internal Medicine; Medical Oncology

I am a board-certified medical oncologist specializing in the treatment of lung cancer and a physician-scientist specializing in computational biology and single-cell genomics, with a focus on small cell transformation in lung and prostate cancer.

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As a clinician, I work in the inpatient setting, where I treat patients who have been admitted to Memorial Hospital. In the hospital, I work closely with a dedicated group of doctors, including world-renowned lung cancer experts, nurses and nurse practitioners, pharmacists, and support staff to deliver the highest-quality care possible. In addition to medical management, I strive to communicate with my patients and their families to ease the burden of uncertainty. Whether you are a patient or a family member, any experience with cancer can be scary. So much of the fear associated with cancer is fear of the unknown, and I will take the time to discuss the rationale and expectations for any diagnostic tests or treatments so that we can banish this fear as much as possible.

As a physician-scientist and computational biologist conducting cancer research at Sloan Kettering Institute (SKI), I aim to gain a better understanding of lineage plasticity, a poorly understood mechanism of therapeutic resistance and metastasis in cancer. A key example of plasticity in cancer is when adenocarcinoma escapes pressure from targeted therapies by transforming into a more aggressive disease called small cell cancer. This phenomenon arises in many different cancer types, including lung, prostate, bladder, uterine, cervical, gastrointestinal tract, and head and neck, among others. I also strive to use single-cell technologies to understand how lineage plasticity in lung and prostate cancer affects tumor progression, and how the surrounding microenvironment can impact this process. The overarching goal of this research is to identify a new class of drugs that can reverse plasticity, thereby restoring the disease’s original sensitivity to targeted therapies.

I completed my undergraduate studies in biomedical computation at Stanford University, my MD/PhD at Columbia University College of Physicians and Surgeons, my residency in internal medicine at Weill Cornell Medical Center at NewYork-Presbyterian, and, finally, my fellowship in oncology at Memorial Sloan Kettering Cancer Center. For my PhD work, I studied computational biology and developed new methods to model the topology of viral evolution and identify gene fusions in cancer. These methods supported the identification of a class of recurrent FGFR-TACC fusions in brain cancer; of note, this was the first time that this mutation was found in any cancer. Now, this mutation is an FDA-approved drug target in bladder and gallbladder cancer.

Awards and Honors

  • Clinical Investigator Award, K08CA259161, National Cancer Institute (2021-Current)
  • Young Investigator Award, American Society of Clinical Oncology & Conquer Cancer Foundation (2021-Current)
  • Lung Cancer Research Fellowship, American Association for Cancer Research (2021)
  • Harborside Endowed Merit Award, American Society of Clinical Oncology & Conquer Cancer Foundation (2021)
  • World Conference on Lung Cancer Early Career Award, International Association for the Study of Lung Cancer (2021)
  • Gerry Fellowship, Alan and Sandra Gerry Metastasis and Tumor Ecosystems Center (2020-2021)
  • Distinguished Young Investigator Award, EGFR Resisters (2020)
  • T32 Investigational Cancer Therapeutics Training Program Grant, Memorial Sloan Kettering (2018-2020)

Colleagues

Doctors at Memorial Sloan Kettering work as teams, with specialists from all different areas. This allows us to consider all your needs together, and to give you the best possible care.

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Clinical Trials

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Find a Clinical Trial for You

Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.

You may be able to participate in a clinical trial even if you are new to MSK. Search our online directory to find trial information and see more about who can participate.

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Research and Publications

Chan JM, Quintanal-Villalonga Á, Gao VR, Xie Y, Allaj V, Chaudhary O, Masilionis I, Egger J, Chow A, Walle T, Mattar M, Yarlagadda DVK, Wang JL, Uddin F, Offin M, Ciampricotti M, Qeriqi B, Bahr A, de Stanchina E, Bhanot UK, Lai WV, Bott MJ, Jones DR, Ruiz A, Baine MK, Li Y, Rekhtman N, Poirier JT, Nawy T, Sen T, Mazutis L, Hollmann TJ, Pe’er D, Rudin CM. Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer. Cancer Cell. 2021 Nov 8;39(11):1479-1496.e18. doi: 10.1016/j.ccell.2021.09.008. Epub 2021 Oct 14. PubMed Central PMCID: PMC8628860.

Offin M, Chan JM, Tenet M, Rizvi HA, Shen R, Riely GJ, Rekhtman N, Daneshbod Y, Quintanal-Villalonga A, Penson A, Hellmann MD, Arcila ME, Ladanyi M, Pe’er D, Kris MG, Rudin CM, Yu HA. Concurrent RB1 and TP53 Alterations Define a Subset of EGFR-Mutant Lung Cancers at risk for Histologic Transformation and Inferior Clinical Outcomes. J Thorac Oncol. 2019 Oct;14(10):1784-1793. doi: 10.1016/j.jtho.2019.06.002. Epub 2019 Jun 19. PubMed Central PMCID: PMC6764905.

Chan JM, Carlsson G, Rabadan R. Topology of viral evolution. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18566-71. doi: 10.1073/pnas.1313480110. Epub 2013 Oct 29. PubMed Central PMCID: PMC3831954.

Singh D, Chan JM, Zoppoli P, Niola F, Sullivan R, Castano A, Liu EM, Reichel J, Porrati P, Pellegatta S, Qiu K, Gao Z, Ceccarelli M, Riccardi R, Brat DJ, Guha A, Aldape K, Golfinos JG, Zagzag D, Mikkelsen T, Finocchiaro G, Lasorella A, Rabadan R, Iavarone A. Transforming fusions of FGFR and TACC genes in human glioblastoma. Science. 2012 Sep 7;337(6099):1231-5. doi: 10.1126/science.1220834. Epub 2012 Jul 26. PubMed Central PMCID: PMC3677224.

Publications on PubMed

Visit PubMed for a full listing of Dr. Chan’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.

See all on PubMed

Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Joseph Minhow Chan discloses the following relationships and financial interests:

  • Mirati Therapeutics
    Ownership / Equity Interests

If you’re a patient at MSK and would like more information about your doctor’s external relationships, please talk with your doctor.

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.

This page and data include information for a specific MSK annual disclosure period (January 1, 2021 through disclosure submission in spring 2022). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].


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