Areas of Expertise

Conditions I Treat

  • Head and neck cancers
  • Salivary gland tumors
  • Thyroid cancer and conditions

My Specialties

  • Early-phase clinical trials
  • Targeted therapy
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Get to Know Me

I’m a medical oncologist who is an expert in the treatment of head and neck cancers, with a focus on thyroid and salivary gland cancers. I’m also an early drug development specialist, which means I test promising new cancer drugs in research studies called clinical trials. I see patients at the David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center (MSK).

My area of focus is targeted therapy. Many thyroid and salivary gland cancers are driven by a single gene change. This may be a mutation or a fusion, in which two genes become joined together. These changes can act like a light switch stuck in the “on” position, telling cancer cells to keep growing. Targeted therapies are drugs designed to fit that specific switch and turn it off.

At MSK, we use tests that look at hundreds of genes to find these changes in a tumor. The results help me match each patient with the treatment most likely to work for their cancer diagnosis. If an approved drug is not the right fit, a clinical trial may offer a new option.                                      

As an early drug development specialist, I care for people with many other types of cancer. Often, the cancer has stopped responding to standard treatments, or there is no standard treatment available. Many patients ask me if a particular clinical trial is right for them. I take the time to explain how each trial works, its possible benefits and risks, and how it fits with their goals.

I know that a cancer diagnosis can feel overwhelming, especially when the cancer is rare. As part of a team that includes head and neck surgeons, radiation oncologists, endocrinologists, and pathologists, I’m committed to offering thoughtful and personal care. Together, we create a treatment plan based on what matters most to you. I want you and your family to feel informed, supported, and confident in every decision.

I’m also a physician-scientist, which means I spend part of my time doing research in the laboratory. My research focuses on targeted treatments that block proteins called tyrosine kinases and GTPases. I study how these drugs work and why some cancers stop responding to them. My goal is to improve the drugs we use today and to design new and better ones.

What I Do at MSK

I'm a head and neck medical oncologist, which is a cancer doctor who specializes in head and neck cancers. This includes cancers of the tonsils, tongue, mouth, lips, larynx, nose, sinuses, salivary glands, and thyroid gland.

I'm an early drug development specialist, which is a scientist who tests new drugs to treat cancer. I have special training in research studies, also known as clinical trials.

  • Assistant Attending Physician
Areas of Expertise

Conditions I Treat

  • Head and neck cancers
  • Salivary gland tumors
  • Thyroid cancer and conditions

My Specialties

  • Early-phase clinical trials
  • Targeted therapy
This list shows some key areas of focus, but it may not cover all expertise. When making an appointment, you will be matched with the best healthcare provider for your needs.
Education & Honors

Education

  • MD, Columbia University Vagelos College of Physicians and Surgeons
  • PhD, Columbia University Graduate School of Arts and Sciences

Residencies

  • Internal Medicine, NewYork-Presbyterian Hospital/Columbia University Irving Medical Center

Fellowships

  • Medical Oncology, Memorial Sloan Kettering Cancer Center

Board Certifications

  • Internal Medicine
  • Medical Oncology

Awards and Honors

  • The Ruth L. Kirschstein NRSA Institutional Research Training Grant (T32), National Cancer Institute (2025-2026)
  • Paul Calabresi Career Development Award for Clinical Oncology (K12), National Cancer Institute (2026-2029)

Insurance Information

Understanding your insurance options is an important part of managing your cancer care. We have relationships with many common healthcare providers and plans.

Learn more about the insurance plans that participate with MSK.

If you don't have health insurance or are worried that your care may not be fully covered, our financial assistance programs may be able to help.

Health plans can change at any time. Call the number on the back of your insurance card to see what your plan covers. Make sure it covers the MSK location where you’ll get care.

If you have questions about insurance, call us at 646-497-9176.

Make an Appointment

Current Patients
Request an appointment by calling your Care Team or messaging them in MSK MyChart.

Contact and Location

Location
New York, NY

Looking to see a doctor at a different location? See all MSK locations.

Colleagues

Doctors at Memorial Sloan Kettering work as teams, with specialists from all different areas. This allows us to consider all your needs together, and to give you the best possible care.

See all Head and Neck Oncology Service doctors

See all Early Drug Development Service doctors

Clinical Trials

Smiling doctors in the lab
Find a Clinical Trial for You

Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.

You may be able to participate in a clinical trial even if you are new to MSK. Search our online directory to find trial information and see more about who can participate.

Search clinical trials

Research and Publications

Publications on PubMed

Visit PubMed for a full listing of Dr. Ye’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.

See all on PubMed